ImmunologybioRxivPreprint
CD244 regulates both innate and adaptive immune axes in melanoma by inhibiting autophagy-mediated M1 macrophage maturation
J. Kim, T.-J. Kim, S. Chae…·K.-M. Lee
This study shows CD244 inhibits macrophage maturation in melanoma, enhancing T cell responses and improving tumor rejection when combined with PD-L1 blockade.
DOI 10.1101/2022.12.01.518620