An ancestral vaccine induces anti-Omicron antibodies by hypermutation
S. Park, J. Choi, Y. Lee…·J. Chung
This study shows that repeated mRNA vaccination leads to BCR hypermutation, enabling antibodies to neutralize Omicron variants.
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3 papers
Recent·Most cited
S. Park, J. Choi, Y. Lee…·J. Chung
This study shows that repeated mRNA vaccination leads to BCR hypermutation, enabling antibodies to neutralize Omicron variants.
C. K. Kang, B. Choi, S. Kim…·I. Jung
This study identifies clonal hematopoiesis as an independent risk factor for severe COVID-19 in previously healthy patients, revealing distinct immunological and epigenetic signatures.
S. I. Kim, J. Noh, S. Kim…·J. Chung
The paper identifies stereotypic VH clonotypes against SARS-CoV-2 RBD in patients and healthy individuals, showing their pre-existing presence in the healthy population.