An ancestral vaccine induces anti-Omicron antibodies by hypermutation
S. Park, J. Choi, Y. Lee…·J. Chung
This study shows that repeated mRNA vaccination leads to BCR hypermutation, enabling antibodies to neutralize Omicron variants.
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5 papers
Recent·Most cited
S. Park, J. Choi, Y. Lee…·J. Chung
This study shows that repeated mRNA vaccination leads to BCR hypermutation, enabling antibodies to neutralize Omicron variants.
C. K. Kang, B. Choi, S. Kim…·I. Jung
This study identifies clonal hematopoiesis as an independent risk factor for severe COVID-19 in previously healthy patients, revealing distinct immunological and epigenetic signatures.
N. van Doremalen, M. C. Letko, R. Fischer…·V. Munster
The paper examines the environmental stability, replication kinetics, and pathogenicity of diverse MERS-CoV strains and SARS-CoV-2, finding variation in stability and pathogenicity among isolates.
S. I. Kim, J. Noh, S. Kim…·J. Chung
The paper identifies stereotypic VH clonotypes against SARS-CoV-2 RBD in patients and healthy individuals, showing their pre-existing presence in the healthy population.
K. H. Kim, J. Kim, M. Ko…·J. Chung
This paper isolates an antibody from a recovered SFTS patient that inhibits multiple SFTSV strains and protects mice from infection, suggesting its potential as a therapeutic agent.