Author

C. Ostiguin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. D. Hoffmann· 2 shared C. Mao· 2 shared D. Fang· 2 shared H. Liu· 2 shared L. El-Shennawy· 2 shared S. Swaminathan· 2 shared Y. Jia· 2 shared Y. Luo· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersImmunology

A. D. Hoffmann

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2 papers

Recent·Most cited

Unique molecular signatures sustained in circulating monocytes and regulatory T cells in Convalescent COVID-19 patients

A. D. Hoffmann, S. Weinberg, S. Swaminathan, S. Chaudhuri, H. Mubarak, M. Schipma, C. Mao, X. Wang, L. El-Shennawy, N. Dashzeveg, J. Wei, P. Mehl, L. Shihadah, C. M. Wai, C. Ostiguin, , D. Fang

This study identifies sustained molecular signatures in monocytes and regulatory T cells in convalescent COVID-19 patients, associated with disease severity.

bioRxiv · Mar 26, 2022Immunology

Circulating ACE2-expressing Exosomes Block SARS-CoV-2 Virus Infection as an Innate Antiviral Mechanism

L. El-Shennawy, A. D. Hoffmann, N. K. Dashzeveg, P. J. Mehl, Z. Yu, V. L. Tokars, V. Nicolaescu, C. Ostiguin, Y. Jia, L. Li, K. Furlong, C. Mao, J. Wysocki, D. Batlle, T. J. Hope, , H. Liu

The paper shows that ACE2-expressing exosomes in plasma block SARS-CoV-2 infection by competing with cellular ACE2, offering a new innate antiviral mechanism.

bioRxiv · Dec 3, 2020Immunology