Author

A. D. Hoffmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

H. Liu· 5 shared L. El-Shennawy· 4 shared Y. Jia· 4 shared D. Fang· 3 shared N. K. Dashzeveg· 3 shared S. Swaminathan· 3 shared Y. Shen· 3 shared B. Wray· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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5 shared papersImmunology

H. Liu

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Author profile →

5 papers

Recent·Most cited

Novel antibody language model accelerates IgG screening and design for broad-spectrum antiviral therapy

H. F. Mubarak, W. Tan, A. D. Hoffmann, Y. Sun, J. Wei, L. El-Shennawy, J. R. Squires, N. K. Dashzeveg, B. Simonton, Y. Jia, R. Iyer, Y. Xu, V. Nicolaescu, D. Elli, G. C. Randall, , Y. Shen

This paper introduces an antibody language model (AbLM) to accelerate IgG screening and design for broad-spectrum antiviral therapy, achieving higher precision in predicting variant-resistant antibodies.

bioRxiv · Mar 1, 2024 · PreprintImmunology

Unique molecular signatures sustained in circulating monocytes and regulatory T cells in Convalescent COVID-19 patients

A. D. Hoffmann, S. Weinberg, S. Swaminathan, S. Chaudhuri, H. Mubarak, M. Schipma, C. Mao, X. Wang, L. El-Shennawy, N. Dashzeveg, J. Wei, P. Mehl, L. Shihadah, C. M. Wai, C. Ostiguin, , D. Fang

This study identifies sustained molecular signatures in monocytes and regulatory T cells in convalescent COVID-19 patients, associated with disease severity.

bioRxiv · Mar 26, 2022Immunology

CD81 partners with CD44 in promoting exosome biogenesis, tumor cluster formation, and lung metastasis in triple negative breast cancer

E. K. Ramos, C.-F. Tsai, N. K. Dashzeveg, Y. Jia, Y. Cao, M. Manu, R. Taftaf, A. D. Hoffmann, L. El-Shennawy, M. A. Gritsenko, V. Adorno-Cruz, E. J. Schuster, D. Scholten, D. Patel, X. Liu, , H. Liu

bioRxiv · Feb 23, 2022Cancer Biology

Circulating ACE2-expressing Exosomes Block SARS-CoV-2 Virus Infection as an Innate Antiviral Mechanism

L. El-Shennawy, A. D. Hoffmann, N. K. Dashzeveg, P. J. Mehl, Z. Yu, V. L. Tokars, V. Nicolaescu, C. Ostiguin, Y. Jia, L. Li, K. Furlong, C. Mao, J. Wysocki, D. Batlle, T. J. Hope, , H. Liu

The paper shows that ACE2-expressing exosomes in plasma block SARS-CoV-2 infection by competing with cellular ACE2, offering a new innate antiviral mechanism.

bioRxiv · Dec 3, 2020Immunology

ITGA2 is a target of miR-206 promoting cancer stemness and lung metastasis through enhanced ACLY and CCND1 expression in triple negative breast cancer

V. Adorno-Cruz, A. D. Hoffmann, X. Liu, B. Wray, R. A. Keri, H. Liu

bioRxiv · Mar 19, 2019Cancer Biology