Author

C. P. Lai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Organism:non-human primate· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

A. Y.-T. Wu· 1 shared B. Carlson· 1 shared B. J. A. Magoling· 1 shared B. Smith· 1 shared E. K. Hutchinson· 1 shared E. N. Shirk· 1 shared G. Lima· 1 shared G. Liu· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Y.-T. Wu

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2 papers

Recent·Most cited

Membrane Protein Modification Modulates Big and Small Extracellular Vesicle Biodistribution and Tumorigenic Potential in Breast Cancers In Vivo

B. J. A. Magoling, A. Y.-T. Wu, Y.-J. Chen, W. W.-T. Wong, S. T.-Y. Chuo, H.-C. Huang, Y.-C. Sung, H.-T. Hsieh, P. Huang, K.-Z. Lee, K.-W. Huang, R.-H. Chen, Y. Chen, C. P. Lai

This study identifies distinct in vivo properties and functions of large and small extracellular vesicles in breast cancer, showing their differential biodistribution and tumorigenic potential.

bioRxiv · Sep 28, 2022 · PreprintCancer Biology

Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to Macaca nemestrina

T. Driedonks, L. Jiang, B. Carlson, Z. Han, G. Liu, S. E. Queen, E. N. Shirk, O. Gololobova, L. H. Nyberg, G. Lima, L. Paniushkina, M. Garcia-Contreras, K. Schonvisky, M. Stover, S. Guerrero-Martin, , K. W. Witwer

This study investigates the pharmacokinetics and biodistribution of extracellular vesicles in macaques via intravenous and intranasal routes, finding longer plasma circulation times and organ uptake with IV administration, but limited systemic distribution with IN.

bioRxiv · Jul 28, 2021Pharmacology & Toxicology