Author

C. Samakovlis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 4 Assay:scRNA-seq· 4 Research Focus:clustering· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. Koepke· 3 shared S. Bellusci· 3 shared A. Liontos· 2 shared S. Herold· 2 shared A. B. Firsova· 1 shared A. Fysikopoulos· 1 shared A. K. Bjorklund· 1 shared A. Lingampally· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCell Biology

J. Koepke

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Lineage-tracing of Acta2+ cells in aged mice during lung fibrosis formation and resolution supports the lipofibroblasts to myofibroblast reversible switch

A. Lingampally, M. Truchi, O. Mauduit, V. Delcroix, S. Hadzic, J. Koepke, A.-I. Vazquez-Armendariz, S. Herold, C. Samakovlis, H. Makarenkova, E. El Agha, C. Chen, B. Mari, S. Bellusci

This study traces Acta2+ cells in aged mice during lung fibrosis to show lipofibroblasts can reversibly switch to myofibroblasts, with similar patterns observed in humans.

bioRxiv · Feb 19, 2024 · PreprintPathology

Postnatal FGFR-signalling establishes gradients of cell identities along the proximal-distal axis of the lung airways

A. Sountoulidis, A. B. Firsova, A. Liontos, J. Theelke, J. Koepke, P. Millar-Buchner, L. Manneras-Holm, A. K. Bjorklund, A. Fysikopoulos, K. Gaengel, F. Backhed, C. Betsholtz, W. Seeger, S. Bellusci, C. Samakovlis

The paper identifies gene-expression gradients along the lung airway axis and shows FGFR-signaling establishes these gradients postnatally.

bioRxiv · Dec 11, 2023 · PreprintCell Biology

Autocrine Sfrp1 inhibits lung fibroblast invasion during transition to injury induced myofibroblasts

C. H. Mayr, A. Sengupta, M. Ansari, J. Pestoni, P. Ogar, I. Angelidis, A. Liontos, J. A. Rodriguez, N. J. Lang, M. Strunz, S. Ashgarpour, D. Gonzalez, M. Gerckens, B. Oehrle, V. Viteri, , H. B. Schiller

The paper identifies Sfrp1 as an autocrine inhibitor of fibroblast invasion during lung fibrosis by analyzing fibroblast states and signaling pathways in mouse lung regeneration.

bioRxiv · Jul 11, 2022Cell Biology

FGF10 triggers de novo alveologenesis in a BPD model: impact on the resident mesenchymal niche cells

S. Taghizadeh, C.-M. Chao, S. Guenther, L. Glaser, L. Gersmann, G. Michel, S. Kraut, K. Goth, J. Koepke, S. Herold, C. Samakovlis, N. Weissmann, g. Aquila, F. Ricci, L. Boyer, , S. Rivetti

This study shows that FGF10 administration rescues alveologenesis defects in a BPD mouse model by activating resident mesenchymal niche cells.

bioRxiv · Mar 14, 2022Cell Biology