Author

D. A. Scheiblin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 3 Organism:mouse· 3 Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:multiome· 1

Frequent Co-Authors

D. A. Wink· 3 shared S. J. Lockett· 3 shared R. J. Bryant· 2 shared V. Somasundaram· 2 shared A. C. Gilmore· 1 shared A. Chatrian· 1 shared A. D. Lamb· 1 shared A. Das· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCancer Biology

D. A. Wink

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Author profile →

4 papers

Recent·Most cited

NOS2 and COX2 Blockade Limits TNBC Disease Progression and Alters CD8+ T Cell Spatial Orientation and Density

V. Somasundaram, L. A. Ridnour, R. Y. S. Cheng, A. J. Walke, N. Kedei, D. D. Bhattacharyya, A. L. Wink, E. F. Edmondson, D. Butcher, A. Warner, T. H. Dorsey, D. A. Scheiblin, W. Heinz, R. J. Bryant, R. Kinders, , D. A. Wink

This paper shows that blocking NOS2 and COX2 reduces TNBC tumor growth and improves CD8+ T cell infiltration and spatial distribution in tumors.

bioRxiv · Jun 3, 2022 · PreprintCancer Biology

3'UTR-directed, kinase proximal mRNA decay inhibits C/EBPβ phosphorylation/activation to suppress senescence in tumor cells

J. Salotti, N. Asif, S. Basu, A. Das, M. Yang, B. Karim, K. Saylor, N. Martin, D. A. Scheiblin, S. Misra, B. Luke, T. Andresson, S. Lockett, L. Tessarollo, P. F. Johnson

This study identifies a mechanism where 3'UTR-directed mRNA decay inhibits C/EBPβ activation, suppressing senescence in tumor cells and promoting tumor progression.

bioRxiv · Mar 29, 2022Cancer Biology

Tumor irradiation combined with vascular-targeted photodynamic therapy enhances anti-tumor effects in preclinical prostate cancer.

H. T. Sjoberg, Y. J. Philippou, A. L. Magnussen, I. D. Tullis, E. Bridges, A. Chatrian, J. Loefebvre, K. H. Tam, E. A. Murphy, J. Rittscher, D. Preise, L. Agemy, T. Yechezkel, S. C. Smart, P. Kinchesh, , R. J. Bryant

This paper investigates combining fractionated radiotherapy with vascular-targeted photodynamic therapy to enhance tumor control in preclinical prostate cancer models.

bioRxiv · Nov 26, 2020 · PreprintCancer Biology

An in vitro tumorigenesis model based on live cell-generated oxygen and nutrient gradients

A. C. Gilmore, S. J. Flaherty, V. Somasundaram, D. A. Scheiblin, S. J. Lockett, D. A. Wink, W. F. Heinz

This paper introduces a 2D live-cell chamber to model the tumor microenvironment, showing that breast cancer cells and macrophages generate hypoxic and nutrient gradients and exhibit spatially varying phenotypes.

bioRxiv · Aug 24, 2020Cancer Biology