Author

P. F. Johnson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:multiome· 2 Approach:statistical model· 2

Frequent Co-Authors

B. Karim· 3 shared K. Saylor· 3 shared N. Martin· 3 shared S. Basu· 3 shared B. Luke· 2 shared J. Salotti· 2 shared S. Lockett· 2 shared S. Misra· 2 shared

Activity by Year

2022-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersCancer Biology

B. Karim

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The lnc-FANCI-2 intrinsically restricts RAS signaling in HPV16-infected cervical cancer

H. Liu, L. Yu, V. Majerciak, T. Meyer, M. Yi, P. F. Johnson, M. Cam, D. R. Lowy, Z.-M. Zheng

This study identifies lnc-FANCI-2 as a regulator of RAS signaling in HPV16-infected cervical cancer, showing its role in lesion progression and patient survival.

bioRxiv · Feb 1, 2024Cancer Biology

Single-cell mRNA-regulation analysis reveals cell type-specific mechanisms of type 2 diabetes

J. Martinez-Lopez, A. Lindqvist, A. Lopez-Pascual, P. Chen, L. Shcherbina, S. Chriett, N. G. Skene, R. B. Prasad, M. Lancien, P. F. Johnson, P. Eliasson, C. Louvet, A. B. Munoz-Manchado, R. Sandberg, J. Hjerling-Leffler, N. Wierup

This study uses single-cell RNA sequencing and network analysis to identify cell type-specific gene dysregulation mechanisms in type 2 diabetes.

bioRxiv · Mar 23, 2023 · PreprintCell Biology

CK2 signaling from TOLLIP-dependent perinuclear endosomes is an essential feature of KRAS and NRAS mutant cancers

S. Basu, B. Luke, B. Karim, N. Martin, S. Lockett, S. Das, T. Andresson, K. Saylor, S. Kozlov, L. Bassel, D. Esposito, M. Galloux, P. F. Johnson

This study identifies TOLLIP as a critical adaptor for CK2 signaling from perinuclear endosomes in KRAS and NRAS mutant cancers, showing its role in tumor proliferation and progression.

bioRxiv · Apr 5, 2022 · PreprintCancer Biology

3'UTR-dependent dynamic changes in TP53 mRNA localization regulate p53 tumor suppressor activity

L. Hu, S. Misra, B. Karim, S. Kuhn, J. Salotti, S. Basu, N. Martin, K. Saylor, P. F. Johnson

This study shows that 3'UTR sequences of TP53 mRNA regulate its localization and activity by modulating CK2 phosphorylation and AMPK2/HuR dynamics.

bioRxiv · Apr 4, 2022 · PreprintCancer Biology

3'UTR-directed, kinase proximal mRNA decay inhibits C/EBPβ phosphorylation/activation to suppress senescence in tumor cells

J. Salotti, N. Asif, S. Basu, A. Das, M. Yang, B. Karim, K. Saylor, N. Martin, D. A. Scheiblin, S. Misra, B. Luke, T. Andresson, S. Lockett, L. Tessarollo, P. F. Johnson

This study identifies a mechanism where 3'UTR-directed mRNA decay inhibits C/EBPβ activation, suppressing senescence in tumor cells and promoting tumor progression.

bioRxiv · Mar 29, 2022Cancer Biology