Author

J. Hsu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 2 Biochemistry· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:imaging· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

C.-T. K. Tseng· 3 shared V. Tat· 3 shared B.-H. Peng· 2 shared P. Saenkham-Huntsinger· 2 shared A. Cheng· 1 shared A. Dimitrakakis· 1 shared A. Drelich· 1 shared A. Griffiths· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMicrobiology

C.-T. K. Tseng

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Patient-Specific Vascularized Tumor Model: Blocking TAM Recruitment with Multispecific Antibodies Targeting CCR2 and CSF-1R

H. T. Nguyen, N. Gurvich, M. R. Gillrie, G. Offeddu, M. Humayun, E. L. Kan, Z. Wan, M. F. Coughlin, C. Zhang, V. Vu, S. W. L. Lee, S.-L. Tan, D. Barbie, J. Hsu, R. D. Kamm

This paper develops a vascularized tumor model to study TAM recruitment and evaluates a multispecific antibody's effect on monocyte migration and TAM repolarization.

bioRxiv · Nov 28, 2023Bioengineering

Characterization of Unique Pathological Features of COVID-Associated Coagulopathy: Studies with AC70 hACE2 Transgenic Mice Highly Permissive to SARS-CoV-2 Infection

A. K. Drelich, K. Rayavara, J. Hsu, P. Saenkham-Huntsinger, B. M. Judy, V. Tat, T. G. Ksiazek, B.-H. Peng, C.-T. K. Tseng

This study characterizes the coagulopathy in AC70 hACE2 transgenic mice infected with SARS-CoV-2, revealing hypercoagulable states and ANXA2 system dysregulation.

bioRxiv · Oct 30, 2023Microbiology

Measuring chondrocyte viability of articular cartilage based on label-free two-photon microscopy and deep learning image analysis

H. Fan, P. Xu, X. Chen, Y. Li, J. Hsu, M. Le, Z. Zhang, E. Ye, B. Gao, T. Ye

This paper develops a deep learning method to assess chondrocyte viability using label-free two-photon microscopy images from rat and porcine cartilage, achieving 95% accuracy.

bioRxiv · Feb 13, 2023 · PreprintBioengineering

A pan-variant mRNA-LNP T cell vaccine protects HLA transgenic mice from mortality after infection with SARS-CoV-2 Beta

B. Carter, P. Huang, G. Liu, Y. Liang, P. J. C. Lin, B.-H. Peng, L. McKay, A. Dimitrakakis, J. Hsu, V. Tat, P. Saenkham-Huntsinger, J. Chen, C. Kaseke, G. D. Gaiha, Q. Xu, , D. K. Gifford

A T cell vaccine based on conserved epitopes protects HLA transgenic mice from SARS-CoV-2 Beta variant mortality without inducing neutralizing antibodies.

bioRxiv · Sep 23, 2022Immunology

Expression and functional evaluation of recombinant human ABO blood group antigen cleaving glycoside hydrolases α-N-acetylgalactosaminidase, α-galactosidase, and endo-β-galactosidase produced in Escherichia coli

W. H. Toh, Y. Kuo, S. K. Hsu, B. Chen, A. J. Lee, E. Liaw, J. Lee, A. Cheng, L. Hwa, K. Hu, S. Chien, C. Wong, K. Chang, M. Hang, S. Hong, , J. Hsu

This study evaluates recombinant glycoside hydrolases for converting A, B, and AB blood types to O by cleaving surface antigens, showing partial success in porcine red blood cells.

bioRxiv · May 4, 2022 · PreprintBiochemistry

Efficient Neutralization of SARS-CoV-2 Omicron and Other VOCs by a Broad Spectrum Antibody 8G3

H. Ma, C.-T. K. Tseng, H. Zong, Y. Liao, Y. Ke, H. Tang, L. Wang, Z. Wang, Y. He, Y. Chang, S. Wang, A. Drelich, J. Hsu, V. Tat, Y. Yuan, , J. Zhu

This study evaluates the neutralization efficacy of antibodies against SARS-CoV-2 Omicron and other variants, finding that antibody 8G3 maintains broad neutralizing activity while EUA antibodies lose effectiveness.

bioRxiv · Feb 25, 2022 · PreprintCell Biology

Characterization of the nanomechanical properties of the fission yeast (Schizosaccharomyces pombe) cell surface by atomic force microscopy

E. Gibbs, J. Hsu, K. Barth, J. W. Goss

This study uses atomic force microscopy to characterize the nanomechanical properties of fission yeast cell surfaces during polarized growth, finding increased elasticity and decreased stiffness at growing cell poles.

bioRxiv · Jan 18, 2021Cell Biology