Author

P. Val

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 2 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Martinez· 4 shared D. Dufour· 4 shared I. Sahut-Barnola· 4 shared A. Levasseur· 3 shared A. M. Lefrancois-Martinez· 3 shared I. Tauveron· 3 shared J.-C. Pointud· 3 shared C. Kamilaris· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersPathology

A. Martinez

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Sexually dimorphic activation of innate antitumour immunity prevents adrenocortical carcinoma development

J. J. Wilmouth, J. Olabe, D. Garcia-Garcia, C. Lucas, R. Guiton, F. Roucher-Boulez, D. Dufour, C. Damon-Soubeyrand, I. Sahut-Barnola, J.-C. Pointud, Y. Renaud, A. Levasseur, I. Tauveron, A.-M. Lefrancois-Martinez, A. Martinez, P. Val

This study shows that sexually dimorphic activation of innate antitumour immunity prevents adrenocortical carcinoma development, with male-specific macrophage responses driving tumour regression.

bioRxiv · Apr 29, 2022 · PreprintCancer Biology

Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation

D. Dufour, T. Dumontet, I. Sahut-Barnola, M. Onzon, E. Pussard, J. Wilmouth, J. Olabe, C. Lucas, A. Levasseur, J.-C. Pointud, F. Roucher-Boulez, I. Tauveron, G. Bossis, D. Breault, E. T. Yeh, , A. Martinez

This study shows that loss of SENP2 causes adrenal cortex zonal defects and glucocorticoid deficiency by disrupting transdifferentiation and signaling pathways.

bioRxiv · Feb 8, 2022 · PreprintPhysiology

Steroidogenic factor-1 lineage origin of skin lesions in Carney complex syndrome

I. Sahut-Barnola, A. M. Lefrancois-Martinez, D. Dufour, J.-M. Botto, C. Kamilaris, F. R. Faucz, C. A. Stratakis, P. Val, A. Martinez

This study identifies dermal fibroblasts as the origin of skin lesions in Carney complex by showing their pro-melanogenic activity under PKA signaling disruption.

bioRxiv · Jan 26, 2022Pathology

PKA drives paracrine crisis and WNT4-dependent testis tumor in Carney complex

C. Djari, I. Sahut-Barnola, A. Septier, I. Plotton, N. Montanier, D. Dufour, A. Levasseur, J. Wilmouth, J.-C. Pointud, F. Faucz, C. Kamilaris, A.-G. Lopez, F. Guillou, A. Swain, S. J. Vainio, , A. M. Lefrancois-Martinez

The paper investigates the role of PKA in Carney complex testis tumors, showing that Prkar1a mutations in both stromal and Sertoli cells drive LCCSCTs via WNT4-dependent paracrine signaling.

bioRxiv · Dec 21, 2020 · PreprintPathology