D. Hajra

Evaporation of bacteria-laden surrogate respiratory fluid droplets: On a hydrophilic substrate versus contact-free environment confers differential bacterial infectivity

This study compares bacterial infectivity in droplet nuclei formed from evaporating respiratory fluid on a hydrophilic substrate versus in a contact-free environment.

SIRT1 and SIRT3 impact host mitochondrial function and host- Salmonella pH balance during infection

This study shows that SIRT1 and SIRT3 regulate mitochondrial function and pH balance in macrophages during Salmonella infection, affecting bacterial gene expression.

A host AAA-ATPase exhibits bacteriolytic activity for clearance of microbial infection

The paper shows that the host AAA-ATPase VCP/p97 has bacteriolytic activity by mechanically extracting ubiquitinated proteins from bacterial membranes, leading to microbial clearance in a mouse sepsis model.

Salmonella-induced SIRT1 and SIRT3 are crucial for maintaining the metabolic switch in bacteria and host for successful pathogenesis

This study shows that Salmonella modulates SIRT1 and SIRT3 to maintain its metabolism and promote pathogenesis by altering host macrophage polarization and metabolism.

The extracellular loops of Salmonella Typhimurium outer membrane protein A (OmpA) maintain the stability of Salmonella containing vacuole (SCV) in murine macrophages and protect the bacteria from autophagy-dependent lysosomal degradation

This study shows that OmpA's extracellular loops stabilize the Salmonella containing vacuole (SCV) and prevent autophagy-mediated degradation in murine macrophages.