Loss of Grem1-articular cartilage progenitor cells causes osteoarthritis.
J. Q. Ng, T. H. Jafarov, C. B. Little, T. Wang, A. Ali, Y. Ma, G. Radford, L. Vrbanac, M. Ichinose, S. Whittle, D. Hunter, T. Lannagan, N. Suzuki, J. M. Goyne, H. Kobayashi, , S. Mukherjee
This study identifies Grem1-articular cartilage progenitor cells as critical for maintaining joint health, and their loss leads to osteoarthritis, with potential therapeutic targeting of FGFR3.
bioRxiv · Mar 29, 2023 · PreprintCell Biology