D. J. Brogan

This paper develops a CRISPR-based sterile insect technique to suppress Aedes aegypti populations by generating sterile males that outcompete wild mosquitoes.

The paper develops REAPER, a Cas13-based antiviral sensor that kills infected mosquitoes upon activation by arbovirus infection.

This study evaluates the use of CasRx, a Cas ribonuclease, for programmable RNA targeting in Drosophila melanogaster, showing transcript targeting, toxicity, and off-target effects.