I. Antoshechkin

This paper develops a precision guided Sterile Insect Technique (pgSIT) for malaria vector control using CRISPR to achieve high male sterility and female lethality in Anopheles gambiae.

The paper introduces SEPARATOR, a method using sex-specific alternative splicing to enable efficient male-only sex separation in Aedes aegypti for genetic biocontrol.

This paper develops a CRISPR-based sterile insect technique to suppress Aedes aegypti populations by generating sterile males that outcompete wild mosquitoes.

The paper develops REAPER, a Cas13-based antiviral sensor that kills infected mosquitoes upon activation by arbovirus infection.

This paper develops a genetic population suppression system in Anopheles gambiae mosquitoes using CRISPR to eliminate female offspring, leading to sustained population reduction.

The paper engineers reproductively isolated species using CRISPR to create threshold-dependent gene drive capabilities in D. melanogaster.

The paper identifies haploidizer, a gene on a B chromosome in Nasonia vitripennis, that mediates genome elimination and sex conversion through testis-specific expression.

This paper develops genetically engineered Aedes aegypti mosquitoes expressing an engineered antibody that broadly neutralizes all four DENV serotypes, significantly reducing viral transmission.