Author

D. Lavillete

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Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

G. Xiao· 1 shared G. Zou· 1 shared H. Li· 1 shared J. Shan· 1 shared K. Lan· 1 shared K. Xu· 1 shared L. Xu· 1 shared L. Zhang· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

G. Xiao

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1 paper

Recent·Most cited

MicrobiologyProtein & CellPeer-reviewedAug 4, 2020

Novel and potent inhibitors targeting DHODH, a rate-limiting enzyme in de novo pyrimidine biosynthesis, are broad-spectrum antiviral against RNA viruses including newly emerged coronavirus SARS-CoV-2

R. Xiong, L. Zhang, S. Li…·K. Xu

This paper identifies two potent DHODH inhibitors with broad-spectrum antiviral activity against RNA viruses, including SARS-CoV-2, and suggests their potential clinical use.

DOI 10.1007/s13238-020-00768-w

experimental assayhost-pathogen & immune response

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