Author

D. Moran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:clustering· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Sundararajan· 3 shared E. G. Pamer· 3 shared M. McMillin· 3 shared A. M. Sidebottom· 2 shared A. Rose· 2 shared C. Woodson· 2 shared E. McSpadden· 2 shared E. Waligurski· 2 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

A. Sundararajan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Protection against Clostridioides difficile disease by a naturally avirulent C. difficile strain

Q. Dong, S. Harper, E. McSpadden, S. S. Son, M.-M. Allen, H. Lin, R. C. Smith, C. Metcalfe, V. Burgo, C. Woodson, A. Sundararajan, A. Rose, M. McMillin, D. Moran, J. Little, , E. G. Pamer

This paper shows that an avirulent C. difficile strain, ST1-75, protects mice from virulent strain-induced colitis by outcompeting it through rapid amino acid depletion, suggesting potential as a biotherapeutic for CDI prevention.

bioRxiv · May 6, 2024 · PreprintMicrobiology

Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species and strain level diversity and evolution

Z. J. Zhang, C. G. Cole, M. Coyne, H. Lin, N. Dylla, R. C. Smith, E. Waligurski, R. Ramaswamy, C. Woodson, V. Burgo, J. Little, D. Moran, A. Rose, M. McMillin, E. Mcspadden, , L. E. Comstock

The paper characterizes a large collection of Bacteroidales isolates from the human gut, revealing genomic and metabolomic diversity and horizontal gene transfer across species.

bioRxiv · Mar 8, 2024Microbiology

Dietary- and host-derived metabolites are used by diverse gut bacteria for anaerobic respiration

A. S. Little, I. T. Younker, M. S. Schechter, P. Nol Bernardino, R. Meheust, J. Stemczynski, K. Scorza, M. W. Mullowney, D. Sharan, E. Waligurski, R. Smith, R. Ramanswamy, W. Leiter, D. Moran, M. McMillin, , S. H. Light

The paper identifies gut bacteria that use dietary and host-derived metabolites as electron acceptors in anaerobic respiration, revealing new metabolic pathways and reductase evolution.

bioRxiv · Dec 26, 2022Microbiology

Independent evolution of influenza A virus H1N1 in pigs in Guatemala

L. Ortiz, G. Geiger, L. Ferreri, D. Moran, D. Alvarez, A. S. Gonzalez-Reiche, D. Mendez, D. S. Rajao, C. Cordon-Rosales, D. R. Perez

The paper identifies independent evolution of H1N1 influenza A viruses in Guatemalan pigs, showing distinct amino acid signatures and genetic lineage from other Central American H1N1 pdm09 viruses.

bioRxiv · Jul 21, 2022 · PreprintEvolutionary Biology