Author

A. Rose

University of Colorado Boulder

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2 Ecology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:clinical cohort / trial· 1

Frequent Co-Authors

A. Sundararajan· 2 shared C. Woodson· 2 shared D. Moran· 2 shared E. G. Pamer· 2 shared E. McSpadden· 2 shared H. Lin· 2 shared J. Little· 2 shared M. McMillin· 2 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

A. Sundararajan

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Divergent climate impacts despite similar response to temperature in a widespread aerial insectivore

Conor Claverie Taff, Jeremy Ryan Shipley, Daniel R. Ardia, David A. Aborn, Lauren Albert, Marc Bélisle, Amos Belmaker, Lisha L. Berzins, Tricia Blake, Frances Bonier, Hannah J. Brewer, Michael W. Butler, Kyle Cameron, Samuel B. Case, David Chang van Oordt, , Maren N. Vitousek

The paper shows that tree swallow populations have similar sensitivity to temperature but differ in vulnerability due to timing constraints and exposure to warming.

bioRxiv · Dec 17, 2025 · PreprintEcology

Protection against Clostridioides difficile disease by a naturally avirulent C. difficile strain

Q. Dong, S. Harper, E. McSpadden, S. S. Son, M.-M. Allen, H. Lin, R. C. Smith, C. Metcalfe, V. Burgo, C. Woodson, A. Sundararajan, A. Rose, M. McMillin, D. Moran, J. Little, , E. G. Pamer

This paper shows that an avirulent C. difficile strain, ST1-75, protects mice from virulent strain-induced colitis by outcompeting it through rapid amino acid depletion, suggesting potential as a biotherapeutic for CDI prevention.

bioRxiv · May 6, 2024 · PreprintMicrobiology

Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species and strain level diversity and evolution

Z. J. Zhang, C. G. Cole, M. Coyne, H. Lin, N. Dylla, R. C. Smith, E. Waligurski, R. Ramaswamy, C. Woodson, V. Burgo, J. Little, D. Moran, A. Rose, M. McMillin, E. Mcspadden, , L. E. Comstock

The paper characterizes a large collection of Bacteroidales isolates from the human gut, revealing genomic and metabolomic diversity and horizontal gene transfer across species.

bioRxiv · Mar 8, 2024Microbiology

Targeting DNA2 Overcomes Metabolic Reprogramming in Multiple Myeloma

N. Thongon, F. Ma, P. Lockyer, N. Baran, J. Liu, C. Jackson, A. Rose, B. Wildeman, M. Marchesini, V. Marchica, P. Storti, N. Giuliani, I. Ganan-Gomez, V. Adema, Y. Qing, , S. Colla

This study identifies DNA2 as a key factor in mitochondrial metabolism that enables multiple myeloma cells to survive DNA damage, showing that targeting DNA2 overcomes metabolic reprogramming and enhances therapy effectiveness.

bioRxiv · Feb 22, 2023Cancer Biology

Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer

S. A. Hutchinson, A. Websdale, P. Lianto, G. Cioccoloni, H. Roberg-Larsen, B. Kim, A. Rose, C. Soteriou, L. M. Wastall, B. Williams, M. Henn, J. J. Chen, L. Ma, J. B. Moore, E. R. Nelson, , J. L. Thorne

This study identifies LXRalpha as a driver of chemoresistance in TNBC through its regulation of P-glycoprotein, linking cholesterol metabolism to chemotherapy failure.

bioRxiv · Aug 4, 2020Cancer Biology