D. P. Giedroc

This paper identifies five CiaR-controlled Ccn sRNAs in S. pneumoniae that modulate Zn resistance and virulence by regulating metal homeostasis and detoxification mechanisms.

This study shows that intracellular persulfide levels reduce HlyU-mediated hemolysin gene activation in V. cholerae by modulating reactive sulfur species sensing.

The paper identifies and characterizes an ABC transporter in Streptococcus pneumoniae that specifically transports ergothioneine, revealing its structure and conservation across bacterial species.

This study investigates the molecular basis of reactive sulfur species specificity in CstR proteins, revealing structural and chemical asymmetry in their reactivity.

The paper identifies structural determinants of persulfide-sensing specificity in SqrR, showing that structural frustration of the disulfide form enhances tetrasulfide bridge formation and persulfide selectivity.

This study presents the structure of FtsX's extracellular loop and shows its essential interaction with PcsB for cell viability in Streptococcus pneumoniae.

The paper identifies residues critical for allosteric activation in a bacterial repressor by analyzing ZnII-induced changes in atomic motions.