N. Verma

The five homologous CiaR-controlled Ccn sRNAs of Streptococcus pneumoniae modulate Zn-resistance.

This paper identifies five CiaR-controlled Ccn sRNAs in S. pneumoniae that modulate Zn resistance and virulence by regulating metal homeostasis and detoxification mechanisms.

Computational modeling of dorsal root ganglion stimulation using an Injectrode

The paper models the Injectrode system to determine how design parameters affect neural activation, finding that larger surface area reduces pain-related activation.

EGFR-to-Src family tyrosine kinase switching in proliferating-DTP TNBC cells creates a hyperphosphorylation-dependent vulnerability to EGFR TKI

This study identifies a hyper-phosphorylation state in drug-resistant TNBC cells caused by EGFR-to-Src kinase switching, making them vulnerable to EGFR TKI treatment.

MPK4 mediated phosphorylation of PIF4 controls thermosensing by regulation of H2A.Z deposition in Arabidopsis

This study shows that MPK4 phosphorylates PIF4, which regulates ARP6 and H2A.Z deposition to control thermosensing in Arabidopsis.

Inherited CDA-I disease: anemia-associated mutations disrupt CDIN1-Codanin1 complex

This study identifies how mutations in CDIN1 and CDAN1 disrupt the CDIN1-Codanin1 complex, contributing to CDA-I disease.

GPX4-VIM equates a proliferating DTP state in TNBC subtypes with converged vulnerabilities to autophagy and glutathione inhibition.

The paper identifies a proliferating DTP state in TNBC subtypes that is vulnerable to autophagy and glutathione inhibition, linking GPX4-VIM expression to survival outcomes.

ClearX9™: an efficient alternative to fetal bovine serum for growing animal cells in vitro

This paper introduces ClearX9 as a sustainable alternative to fetal bovine serum for growing animal cells in vitro, showing comparable growth and health benefits.

Characterization and Applications of Evoked Responses During Epidural Electrical Stimulation

This paper characterizes evoked responses during epidural electrical stimulation and shows how the ECAP component can detect lead migration and muscle activation.

Statin-mediated reduction in mitochondrial cholesterol primes an anti-inflammatory response in macrophages by upregulating JMJD3

This study shows statins reduce macrophage cholesterol, upregulate JMJD3, and shift macrophage activation toward anti-inflammatory responses in both M1 and M2 states.

Microneurography as a Minimally Invasive Method to Assess Target Engagement During Neuromodulation

This study compares microneurography electrodes to cuff and LIFE electrodes in measuring neural signals during neuromodulation, finding microneurography can detect activation thresholds and sensory activity.

Reducing Cholesterol in Resting Macrophage Activates NF-kB through Mitochondria, Resulting in Epigenomic Reprogramming to Dampen Inflammation in Activated Macrophages

A system for CBAF reconstitution reveals roles for BAF47 domains and BCL7 in nucleosome ejection

The paper develops a system for CBAF reconstitution and creates a nucleosome ejection assay, revealing roles for BAF47 domains and BCL7 in nucleosome ejection.

Augmented Transcutaneous Stimulation Using an Injectable Electrode

This paper presents an electroquasistatic model to improve transcutaneous power delivery to an injectable electrode by accounting for capacitive and resistive mechanisms.

A novel positive feedback mechanism of ABI5 phosphorylation by mitogen activated protein kinase-3 regulates ABA signaling in Arabidopsis

This study identifies a positive feedback loop where ABI5 phosphorylation by MAP kinase-3 modulates ABA signaling in Arabidopsis, affecting seed germination and drought tolerance.

Assessment of Proton-Coupled Conformational Dynamics of SARS and MERS Coronavirus Papain-like Proteases: Implication for Designing Broad-Spectrum Antiviral Inhibitors

This study calculates pKa values and assesses proton-coupled conformational dynamics of SARS-CoV-2, SARS-CoV, and MERS-CoV PLpros to inform the design of broad-spectrum antiviral inhibitors.

Magnetoelectric materials for miniature, wireless neural stimulation at therapeutic frequencies

This paper demonstrates magnetoelectric materials enable miniature, wireless neural stimulators operating at therapeutic high-frequencies for treating Parkinson's disease in rodents.

Role of Sulphate Transporter (PiSulT) of Endophytic Fungus Serendipita indica in Plant Growth and Development

The study characterizes PiSulT, a high-affinity sulphate transporter in Serendipita indica, showing its role in sulphate transfer to plants under low sulphate conditions, enhancing plant growth and development.

Mycobacterial OtsA structures unveil substrate preference mechanism and allosteric regulation by 2-oxoglutarate and 2-phosphoglycerate

The paper reports the first mycobacterial OtsA structures from M. thermoresistibile, revealing substrate preference mechanism and allosteric regulation by 2-oxoglutarate and 2-phosphoglycerate.