N. Marr

The interfascicular matrix of energy storing tendons houses heterogenous cell populations disproportionately affected by ageing

This study identifies IFM-resident cell populations in tendons and shows their age-related changes through single-cell RNA sequencing.

The tendon interfascicular basement membrane provides a vascular niche for CD146+ pericyte cell subpopulations

This study identifies CD146+ pericyte subpopulations in the tendon interfascicular basement membrane as a vascular niche involved in tendon structure and function, but not stem cell-like properties.

Virome-wide serological profiling reveals association of herpesviruses with obesity

This study uses ViScan to find HSV-1 and Rhinovirus A associations with obesity in Qatari adults, but not children.

Human T-bet governs innate and innate-like adaptive IFN-γ immunity against mycobacteria

This study identifies T-bet deficiency as a cause of mycobacterial disease by impairing IFN-γ production in innate and innate-like adaptive lymphocytes.

Distinct antibody repertoires against endemic human coronaviruses in children and adults

The paper analyzes antibody repertoires against endemic human coronaviruses in children and adults, finding distinct epitope targets and cross-reactivity patterns.

Bimodal Whole-Mount Imaging Of Tendon Using Confocal Microscopy And X-Ray Micro-Computed Tomography

This paper develops a bimodal imaging technique combining confocal microscopy and x-ray micro-CT to analyze tendon structure in rats and horses, revealing laminin-4 networks and enabling quantitative substructure analysis.

A curated transcriptome dataset collection to investigate inborn errors of immunity.

The paper compiles a curated transcriptome dataset collection from PID patients and controls to enable meta-analysis and improve understanding of inborn errors of immunity.

The abundance of Nudix hydrolase 16 transcripts is elevated in human sepsis: perspectives gained during a hands-on reductionist investigation workshop.

The paper investigates NUDT16 transcript abundance in sepsis using omics data and public datasets, finding elevated levels in septic patients compared to controls.

IRF4 haploinsufficiency in a family with Whipples disease

This study identifies IRF4 haploinsufficiency as the genetic cause of Whipples disease in a family, showing age-dependent incomplete penetrance and chronic Tw carriage preceding disease onset.