Author

D. Spector

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

P. Naik· 2 shared A. Dobin· 1 shared A. Frewen· 1 shared A. Gavryushkin· 1 shared A. S. Almeida· 1 shared A. Yu· 1 shared B. A. Benz· 1 shared B. Liu· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCell Biology

P. Naik

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Author profile →

5 papers

Recent·Most cited

A sub-set of guanine- and cytosine-rich genes are actively transcribed at the nuclear Lamin B1 region

G. I. Balasooriya, P. Naik, T. L. Wee, D. Spector

The paper identifies a subset of actively transcribed genes associated with Lamin B1 at the nuclear envelope in mESCs, showing enrichment of guanine and cytosine in their gene bodies and promoters.

bioRxiv · Oct 28, 2023Cell Biology

Testing for phylogenetic signal in single-cell RNA-seq data

J. C. Moravec, R. Lanfear, D. Spector, S. Diermeier, A. Gavryushkin

This study shows that scRNA-seq data can be used for phylogenetic analysis, revealing tumor clonal composition through expression levels and SNVs.

Journal of Computational Biology · Apr 18, 2023Peer-reviewedCancer Biology

Identification of glioblastoma stem cell-associated lncRNAs using single-cell RNA-sequencing datasets

R. Hazra, R. Utama, P. Naik, A. Dobin, D. Spector

This study identifies GSC-associated lncRNAs using single-cell RNA-sequencing data from GBM tumors and organoids, revealing distinct lncRNA expression patterns in different GSC populations.

bioRxiv · Jan 20, 2023Cancer Biology

Activating a collaborative innate-adaptive immune response to control breast and ovarian cancer metastasis

L. Sun, T. Kees, A. S. Almeida, B. Liu, X.-Y. He, D. Ng, D. Spector, I. M. McNeish, P. Gimotty, S. Adams, M. EGEBLAD

This study shows that combining MPLA and IFNγ reprograms macrophages to kill cancer cells and reduce metastasis in breast and ovarian cancer models.

Cancer Cell · Oct 1, 2021Peer-reviewedCancer Biology

The long non-coding RNA MaTAR20 promotes mammary tumor growth by regulating angiogenesis pathways

S. D. Diermeier, K.-C. Chang, A. Frewen, P. Taaffe, J. C. Grans, H. Xiong, B. A. Benz, S. Russo, D. Nowak, S. Hearn, A. Yu, J. E. Wilkinson, F. Rigo, D. Spector

This study identifies MaTAR20 as a lncRNA that promotes mammary tumor growth by regulating angiogenesis pathways, specifically through its interaction with Tnfsf15.

bioRxiv · Mar 30, 2021 · PreprintCancer Biology