D. Vertommen

skNAC is a Key Driver of Cardiomyocyte Integrity Against Pathological Cardiac Hypertrophy and Heart Failure

This study identifies skNAC as critical for maintaining cardiomyocyte integrity and preventing heart failure by regulating proteome homeostasis and metabolic adaptation during pathological hypertrophy.

The nuclear sulfenome of Arabidopsis: spotlight on histone acetyltransferase GCN5 regulation through functional thiols

This study identifies 225 redox-active nuclear proteins in Arabidopsis, including GCN5, modified by sulfenylation under oxidative stress, revealing their functional impact on protein interactions.

MEDIATOR SUBUNIT 25 modulates ERFVII-controlled hypoxia responses in Arabidopsis

This study identifies AtMED25 as a key mediator of ERFVII-controlled hypoxia responses in Arabidopsis, showing its role in transcriptional regulation under low-oxygen conditions.

Protein kinase Sut1 from the Crenarchaeon Sulfolobus acidocaldarius displays tyrosine phosphorylation activity

The paper identifies and characterizes Sut1, a tyrosine kinase in Sulfolobus acidocaldarius, showing it phosphorylates tyrosine residues in vitro and belongs to a novel archaeal kinase family.

Transcriptional and translational dynamics underlying heat shock response in the thermophilic Crenarchaeon Sulfolobus acidocaldarius

This study investigates the heat shock response in Sulfolobus acidocaldarius using transcriptomic and proteomic analyses, revealing post-transcriptional and post-translational regulation mechanisms.

Cardiovirus leader proteins retarget RSK kinases toward alternative substrates to perturb nucleocytoplasmic traffic

The paper shows Cardiovirus leader protein redirects RSK kinases to phosphorylate nucleoporins, disrupting nucleocytoplasmic transport.

A molecular plugin rescues GroEL/ES substrates from pre-folding oxidation

This study identifies CnoX as a redox quality-control plugin for GroEL, showing it binds outside the substrate-binding site and forms mixed-disulfides with substrates.

Periplasmic oxidized-protein repair during copper stress in E. coli: a focus on the metallochaperone CusF.

This study shows that copper stress in E. coli activates the CusSR system to induce MsrPQ, which repairs oxidized methionine residues in CusF, maintaining copper efflux pump function.

Exostosin-1 Glycosyltransferase Regulates Endoplasmic Reticulum Architecture and Dynamics

This study shows that Exostosin-1 glycosyltransferase regulates ER morphology and dynamics, affecting cell size and metabolic processes in mammalian cells.

SETD3 protein is the actin-specific histidine N-methyltransferase

This study identifies SETD3 as the actin-specific histidine N-methyltransferase in vertebrates, showing it methylates β-actin at H73 and affects actin dynamics and glycolytic activity.