D. Wenzel

In-situ architecture of the human prohibitin complex

This study determines the molecular organisation of the human prohibitin complex within the mitochondrial inner membrane using structural biology methods.

Deficiency in hyaluronan synthase 3 attenuates ruptures in a murine model of abdominal aortic aneurysms by reduced aortic monocyte infiltration

This study shows that deficiency in HAS3 reduces aortic ruptures in a murine AAA model by decreasing monocyte infiltration and ECM degradation.

Inhibition of myeloperoxidase prevents thoracic aortic aneurysm formation in Marfan mice

This study shows that inhibiting myeloperoxidase prevents thoracic aortic aneurysms in Marfan mice by reducing inflammation and extracellular matrix damage.