Author

K. Koehrer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. P. M. Weber· 2 shared P. Petzsch· 2 shared P. Westhoff· 2 shared A. Brueckner· 1 shared A. K. Kondadi· 1 shared A. Koenigs· 1 shared A. Pacholewska· 1 shared A. Rehm· 1 shared

Activity by Year

2022-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersEcology

A. P. M. Weber

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The host genotype actively shapes its microbiome across generations

L. Benga, A. Rehm, C. Gougoula, P. Westhoff, T. Wachtmeister, W. P. M. Benten, E. Engelhardt, A. P. M. Weber, K. Koehrer, M. Sager, S. Janssen

The paper investigates how host genetics shape microbiome composition across generations, finding that host genotype has a stronger influence than maternal legacy after the first generation.

bioRxiv · Mar 14, 2024Ecology

Long-read transcriptome sequencing of CLL and MDS patients uncovers molecular effects of SF3B1 mutations

A. Pacholewska, M. Lienhard, M. Brueggemann, H. Haenel, L. Bilalli, A. Koenigs, K. Becker, K. Koehrer, J. Kaiser, H. Gohlke, N. Gattermann, M. Hallek, C. D. Herling, J. Koenig, C. Grimm, , M. R. Schweiger

This study uses long-read transcriptome sequencing to analyze SF3B1 mutations in CLL and MDS patients, revealing common splicing alterations and their impact on disease prognosis.

bioRxiv · Jan 26, 2024Cancer Biology

Direct excitatory synapses between neurons and tumor cells drive brain metastatic seeding of breast cancer and melanoma

V. Venkataramani, M. A. Karreman, L. C. Nguyen, C. Tehranian, N. Hebach, C. Mayer, L. Meyer, S. Mughal, G. Reifenberger, J. Felsberg, K. Koehrer, M. C. Schubert, D. Westphal, M. Breckwolt, B. Brors, , F. Winkler

The paper shows neurons form direct excitatory synapses with brain-metastatic breast and melanoma cancer cells, supporting metastasis and offering new therapeutic targets.

bioRxiv · Jan 8, 2024 · PreprintCancer Biology

Mitochondrial Apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways

M. Lubeck, R. Naha, Y. Schaumkessel, P. Westhoff, A. Stefanski, P. Petzsch, K. Stuehler, K. Koehrer, A. P. M. Weber, R. Anand, A. S. Reichert, A. K. Kondadi

The paper shows MIC26 regulates metabolic pathways by modulating mitochondrial metabolite exchange, with its role reversing under hyperglycemia.

bioRxiv · Dec 1, 2023 · PreprintCell Biology

Deficiency in hyaluronan synthase 3 attenuates ruptures in a murine model of abdominal aortic aneurysms by reduced aortic monocyte infiltration

T. Suvorava, F. Brack, J. Kaczur, P. Petzsch, K. Koehrer, C. Quast, N. Gerdes, K. Voigt, M. Krueger, J. Fischer, A. Brueckner, B. K. Fleischmann, D. Wenzel, L.-M. A. Zimmermann, G. Sengle, , M. Grandoch

This study shows that deficiency in HAS3 reduces aortic ruptures in a murine AAA model by decreasing monocyte infiltration and ECM degradation.

bioRxiv · Dec 1, 2022 · PreprintImmunology