Author

A. Canella

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

E. R. Mardis· 2 shared G. Nigita· 2 shared P. Rajappa· 2 shared S. Rajendran· 2 shared A. Gross· 1 shared A. Haffey· 1 shared A. Serin Harmanci· 1 shared C. Peterson· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

E. R. Mardis

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genetically modified IL-2 bone marrow-derived myeloid cells reprogram the glioma immunosuppressive tumormicroenvironment

A. Canella, M. Nazzaro, S. Rajendran, C. Schmitt, A. Haffey, G. Nigita, D. Thomas, H. Wrightnour, P. Fadda, E. R. Mardis, T. P. Cripe, P. Rajappa

This study shows that genetically modified myeloid cells releasing IL-2 can reprogram the glioma tumor microenvironment to enhance anti-tumor immunity in a mouse model.

bioRxiv · Oct 19, 2022 · PreprintCancer Biology

Long-term ketogenic diet increases expression of SOX2-dependent oligodendrocyte- and myelination-associated genes in the aged mouse brain.

M. Stratton, J. A. Lopez-Dominguez, A. Canella, J. J. Ramsey, G. A. Cortopassi

This study finds that a long-term ketogenic diet increases SOX2-dependent oligodendrocyte and myelination gene expression in aged mouse brains.

bioRxiv · Feb 22, 2022 · PreprintPhysiology

Single-cell RNA Sequencing Reveals Immunosuppressive Myeloid Cell Diversity and Restricted Cytotoxic Effector Cell Trafficking and Activation During Malignant Progression in Glioma

S. Rajendran, C. Peterson, A. Canella, Y. Hu, A. Gross, M. Cam, A. Serin Harmanci, R. Distefano, G. Nigita, W. Wang, K. E. Miller, O. Elemento, R. D. Roberts, E. C. Holland, G. Rao, , P. Rajappa

This study uses single-cell RNA sequencing to analyze immune cell changes during glioma progression, identifying immunosuppressive myeloid cell subsets and potential therapeutic targets.

bioRxiv · Sep 24, 2021 · PreprintCancer Biology