E. L. Aiden

Depletion of lamins B1 and B2 alters chromatin mobility and induces differential gene expression by a mesoscale-motion dependent mechanism

This study shows that depleting lamins B1 and B2 changes chromatin mobility and gene expression through mesoscale-motion dependent mechanisms.

Convergent selection on juvenile hormone signaling is associated with the evolution of eusociality in bees

The paper identifies genomic signatures and loci associated with convergent gains and losses of eusociality in sweat bees, linking them to juvenile hormone signaling proteins.

Chromosome size affects sequence divergence between species through the interplay of recombination and selection

The paper investigates how chromosome size influences sequence divergence between species by analyzing empirical data and evolutionary simulations across mammalian clades.

Limited evidence for parallel evolution among desert adapted Peromyscus deer mice

The paper examines genome evolution in desert-adapted Peromyscus mice and finds limited evidence for parallel evolution, suggesting divergent molecular mechanisms of adaptation.

Exploring Chromosomal Structural Heterogeneity AcrossMultiple Cell Lines

The paper uses simulations and machine learning to predict chromosomal structures across cell lines, showing consistency with microscopy and revealing conformational transitions and compartment rearrangements.

ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL

The paper shows that ESCO1 and CTCF protect cohesinSTAG1 from WAPL, enabling long chromatin loops that persist during G1-phase.