Author

E. Sohlberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:scRNA-seq· 3 Research Focus:clustering· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

K.-J. Malmberg· 4 shared A. Pfefferle· 3 shared J. P. Goodridge· 3 shared T. Clancy· 3 shared E. H. Ask· 2 shared S. Lorenz· 2 shared a. horowitz· 1 shared B. Jacobs· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersImmunology

K.-J. Malmberg

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4 papers

Recent·Most cited

Targeting HLA-E Positive Cancers with a Novel NKG2A/C Switch Receptor

M. L. Saetersmoen, I. Kotchetkov, L. Torralba-Raga, J. Masilla-Soto, E. Sohlberg, S. Z. Krokeide, Q. Hammer, M. Sadelain, K.-J. Malmberg

This paper develops a novel chimeric A/C switch receptor to target HLA-E positive cancers, showing enhanced anti-tumor activity while avoiding off-tumor toxicity.

bioRxiv · Dec 14, 2023 · PreprintImmunology

Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping

H. K. Netskar, A. Pfefferle, J. P. Goodridge, E. Sohlberg, O. Dufva, S. Teichmann, T. Clancy, a. horowitz, K.-J. Malmberg

The paper creates a single-cell reference map of NK cells and identifies tumor-associated states predictive of patient outcomes in melanoma and osteosarcoma.

bioRxiv · Oct 26, 2023Immunology

A Temporal Transcriptional Map of Human Natural Killer Cell Differentiation

A. Pfefferle, H. Netskar, E. H. Ask, S. Lorenz, J. P. Goodridge, E. Sohlberg, T. Clancy, K.-J. Malmberg

This study maps the transcriptional changes during human NK cell differentiation using single-cell RNA sequencing, identifying key gene programs and checkpoints.

bioRxiv · May 7, 2019 · PreprintImmunology

Intra-lineage Plasticity and Functional Reprogramming Maintain Natural Killer Cell Repertoire Diversity

A. Pfefferle, B. Jacobs, E. H. Ask, S. Lorenz, T. Clancy, J. P. Goodridge, E. Sohlberg, K.-J. Malmberg

The paper uses flow cytometry and single-cell RNA sequencing to show intra-lineage plasticity and functional reprogramming maintain NK cell repertoire diversity during IL-15-driven homeostasis.

bioRxiv · Jan 9, 2019Immunology