F. Al-Shahrour

The paper develops a standardized data model for cancer genomics to enable interoperable data sharing across countries.

This study identifies PD-L2 as a marker of therapy-induced senescent cells that suppress chemotherapy efficacy, showing PD-L2 blockade enhances tumour remission in mice.

The paper develops PD-L1ATTAC mice to study PD-L1-expressing cells' role in cancer and immunity, finding their elimination enhances antitumor immunity and worsens septic responses.

This study shows that FBXW7 deficiency causes multidrug resistance, which can be overcome by targeting mitochondria and activating the Integrated Stress Response.

This study profiles the transcriptome of bone marrow stromal subsets across development, aging, and inflammation in mice, revealing dynamic transcriptional changes and their link to hematopoietic function.