Author

K. McCormick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Microbiology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Organism:human· 5 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

A. L. Harris· 3 shared S.-J. Fan· 3 shared C. Cunningham· 2 shared C. Wilson· 2 shared D. C. I. Goberdhan· 2 shared F. Hamdy· 2 shared J. D. Mason· 2 shared A. Bauer· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

A. L. Harris

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Stress-induced Rab11a-exosomes induce AREG-mediated cetuximab resistance in colorectal cancer

J. D. Mason, E. Marks, S.-J. Fan, K. McCormick, C. Wilson, A. L. Harris, F. C. Hamdy, C. Cunningham, D. C. I. Goberdhan

This paper shows that stress-induced Rab11a-exosomes carrying AREG promote cetuximab resistance in colorectal cancer by activating EGFR signaling in KRAS-wild type cells.

bioRxiv · Dec 19, 2023 · PreprintCancer Biology

Adaptation of a transmitted/founder simian-human immunodeficiency virus for enhanced replication in rhesus macaques

A. Bauer, E. Lindemuth, J. Joy, F. E. Marino, S. S. Docken, R. Krause, S. Mallick, K. McCormick, C. Holt, I. Georgiev, B. K. Felber, B. F. Keele, R. Veazey, M. P. Davenport, H. Li, , K. J. Bar

This paper adapts a transmitted/founder SHIV to enhance replication in rhesus macaques while preserving HIV-1 Env biology, resulting in a more fit virus for NHP HIV studies.

bioRxiv · Dec 12, 2022Microbiology

Antigen-driven clonal selection shapes the persistence of HIV-1 infected CD4+ T cells in vivo

F. R. Simonetti, H. Zhang, G. P. Soroosh, J. Duan, K. Rhodehouse, A. L. Hill, S. A. Beg, K. McCormick, H. Raymond, C. L. Nobles, J. Everett, K. J. Kwon, J. A. White, J. Lai, J. B. Margolick, , R. F. Siliciano

This study links antigen responsiveness, proviral sequences, integration sites, and TCRβ sequences to show antigen-driven clonal selection maintains HIV-1 persistence in CD4+ T cells.

bioRxiv · Dec 1, 2020Microbiology

Anti-androgens induce Rab11a-exosome secretion in prostate cancer by suppressing amino acid-sensitive PAT4-mTORC1 signalling

K. McCormick, P. Sanitt, S.-J. Fan, J. D. Mason, A. L. Harris, F. Hamdy, C. Verrill, R. J. Bryant, D. C. I. Goberdhan

This study shows anti-androgens increase Rab11a-exosome secretion in prostate cancer by inhibiting PAT4-mTORC1 signaling, contributing to drug resistance.

bioRxiv · Sep 18, 2020 · PreprintCancer Biology

Glutamine deprivation regulates the origin and function of cancer cell exosomes

D. Goberdhan, S.-J. Fan, B. Kroeger, P. Marie, E. Bridges, J. Mason, K. McCormick, C. Zois, H. Sheldon, N. Khalid Alham, E. Johnson, M. Elis, I. Stefana, C. Mendes, M. Wainwright, , C. Wilson

This study shows that glutamine deprivation increases exosome release from cancer cells, which promote tumor growth and blood vessel networks through Rab11a-dependent mechanisms.

bioRxiv · Dec 2, 2019Cancer Biology

Sera from individuals with narrowly focused influenza virus antibodies rapidly select viral escape mutations in ovo

A. K. F. Davis, K. McCormick, M. E. Gumina, J. Petrie, E. T. Martin, K. S. Xue, J. D. Bloom, A. Monto, F. Bushman, S. E. Hensley

The paper shows that sera from humans with narrowly focused influenza virus antibodies select for single HA escape mutations in ovo, reducing antibody binding.

bioRxiv · May 17, 2018Microbiology