Author

F. J. Sigworth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

A. Rivetta· 1 shared E. Karakas· 1 shared G. Salazar de Simone· 1 shared J. P. Nicola· 1 shared K. Allen· 1 shared L. M. Amzel· 1 shared M. A. Bianchet· 1 shared N. Carrasco· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

A. Rivetta

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2 papers

Recent·Most cited

BiophysicsbioRxivJun 2, 2023

Cryo-EM structures of Kv1.2 potassium channels, conducting and non-conducting

Y. Wu, Y. Yan, Y. Yang…·F. J. Sigworth

The paper presents cryo-EM structures of Kv1.2 potassium channels in different states, revealing new insights into selectivity filter stability and toxin block mechanisms.

DOI 10.7554/elife.89459

mousecryo-EM

𝕏 PostBluesky

BiophysicsbioRxivApr 7, 2022

Structural insights into the mechanism of the sodium/iodide symporter (NIS)

S. Ravera, J. P. Nicola, G. Salazar de Simone…·N. Carrasco

This study reports three cryo-EM structures of rat NIS, revealing substrate binding sites and transport mechanisms, and provides insights into anion selection and translocation.

DOI 10.1038/s41586-022-05530-2

ratcryo-EM

𝕏 PostBluesky