F. Tesson

A family of lanthipeptides with anti-phage function

The paper identifies a family of over 2000 lanthipeptide biosynthetic gene clusters in Actinobacteria with anti-phage function, demonstrating their conservation and novel compound production.

Strain intrinsic properties and environmental constraints together shape Escherichia coli dynamics and diversity over a twenty-year human gut time series

This study tracks E. coli dynamics in a human gut over 20 years, showing how strain properties and environmental factors influence diversity and persistence.

Viral proteins activate PARIS-mediated tRNA degradation and viral tRNAs rescue infection

The paper shows that viral proteins activate PARIS-mediated tRNA degradation, and viral tRNAs rescue infection by preventing cleavage.

Predicting phage-bacteria interactions at the strain level from genomes

This paper predicts phage-bacteria interactions at the strain level using genomic data from Escherichia isolates and shows tailored phage cocktails are more effective.

Viperin immunity evolved across the tree of life through serial innovations on a conserved scaffold

This study investigates the evolution of viperin genes across prokaryotes and eukaryotes, revealing their conservation, diversification mechanisms, and immune functions.

Genomic characterization of the antiviral arsenal of Actinobacteria

This study systematically identifies anti-phage defense systems in Actinobacteria using DefenseFinder, revealing differences in system distribution and prevalence compared to other bacteria.

Systematic and quantitative view of the antiviral arsenal of prokaryotes

The paper develops DefenseFinder to systematically analyze anti-phage systems in prokaryotes, revealing average of five systems per genome across 20,000 genomes.