D. Rozen

A family of lanthipeptides with anti-phage function

The paper identifies a family of over 2000 lanthipeptide biosynthetic gene clusters in Actinobacteria with anti-phage function, demonstrating their conservation and novel compound production.

Bacterial heterozygosity promotes survival under multidrug selection

This study shows that bacterial heterozygosity increases survival under multidrug selection by allowing flexible chromosome ratio adjustments, reducing fitness costs compared to homozygous cells.

Factors that influence the caste ratio in a bacterial division of labour

The paper investigates how environmental and competitive factors influence mutation frequencies in Streptomyces coelicolor colonies, showing that these frequencies are dynamic and responsive to the competitive environment.

Reversible bacteriophage resistance by shedding the bacterial cell wall

This study shows bacteria can shed their cell wall to resist phage infection, remaining viable under osmoprotective conditions and reverting to a walled state, which may limit phage therapy effectiveness.

Generating heterokaryotic cells via bacterial cell-cell fusion

This study generates heterokaryotic bacterial cells through controlled cell-cell fusion using synthetic lipopeptides, revealing membrane fluidity and specificity as key factors.

Manganese complex Br increases antibiotic sensitivity in multidrug resistant Streptococcus pneumoniae

This study shows that the Mn complex [Mn(CO)3(tpa-κ3N)]Br increases antibiotic sensitivity in multidrug-resistant Streptococcus pneumoniae in vitro and in vivo.

Antibiotic production in Streptomyces is organized by a division of labour through terminal genomic differentiation

The paper shows that Streptomyces coelicolor colonies use division of labour to enhance antibiotic production by generating specialized mutants that trade individual fitness for increased secondary metabolite diversity and yield.

Eavesdropping and crosstalk between quorum sensing peptide signals that regulate bacteriocin production in Streptococcus pneumoniae

The paper investigates social interactions in Streptococcus pneumoniae by analyzing QS signals and receptors, revealing eavesdropping and crosstalk that influence bacteriocin production.

Gut microbiota in the burying beetle, Nicrophorus vespilloides, provide colonization resistance against larval bacterial pathogens

This study shows that the gut microbiome of Nicrophorus vespilloides larvae outcompetes carcass-derived bacteria and provides resistance against the pathogen Serratia marcescens.

Colonization and transmission of the gut microbiotaof the burying beetle, Nicrophorus vespilloides,through development

This study investigates how parental care influences the transmission and persistence of gut bacteria in burying beetle larvae, finding that pre-hatch care is sufficient for symbiont transfer and that larvae become aposymbiotic during pupation.