Author

F. Werner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Approach:statistical model· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Forsthuber· 1 shared A. Kashyap· 1 shared A. Korosec· 1 shared A. Plueckthun· 1 shared A. Soler Cardona· 1 shared A. Zippelius· 1 shared B. Aschenbrenner· 1 shared B. Gesslbauer· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Forsthuber

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cancer associated fibroblast subtypes modulate the tumor-immune microenvironment and are associated with skin cancer malignancy

A. Forsthuber, B. Aschenbrenner, A. Korosec, T. Jacob, K. Annusver, N. Krajic, D. Kholodniuk, S. Frech, S. Zhu, K. Purkhauser, K. Lipp, F. Werner, V. Nguyen, J. Griss, W. Bauer, , B. M. Lichtenberger

This study identifies three CAF subtypes in skin cancers and shows their association with tumor malignancy and immune modulation.

bioRxiv · May 3, 2023Cancer Biology

Cbp1-Cren7 chromatinization of CRISPR arrays favours transcription from leader- over cryptic promoters

F. Blombach, M. Sykora, J. Case, X. Feng, D. P. Baquero, T. Fouqueau, D. K. Phung, D. Barker, M. Krupovic, Q. She, F. Werner

The paper shows that Cbp1-Cren7 chromatinization suppresses cryptic promoter activity and enhances transcription from leader promoters in CRISPR arrays.

bioRxiv · Mar 24, 2023 · PreprintMicrobiology

A prebiotic basis for ATP as the universal energy currency

S. Pinna, C. Kunz, S. Harrison, S. F. Jordan, J. Ward, F. Werner, N. Lane

This paper investigates the prebiotic chemistry of ATP, showing that acetyl phosphate could have driven protometabolism before ATP synthesis and that Fe3+ ions favor ADP phosphorylation to ATP.

bioRxiv · Oct 6, 2021 · PreprintBiochemistry

African Swine Fever Virus and host response - transcriptome profiling of the Georgia 2007/1 strain and porcine macrophages

G. Cackett, R. Portugal, D. Matelska, L. Dixon, F. Werner

This study uses CAGE-seq to analyze the transcriptome of ASFV Georgia 2007/1 in porcine macrophages, identifying virulent-specific transcripts and host gene regulation changes during infection.

bioRxiv · Jul 26, 2021Microbiology

Adaptive anti-tumor immunity is orchestrated by a population of CCL5-producing tissue-resident NK cells

N. Kirchhammer, M. P. Trefny, M. Natoli, D. Bruecher, S. N. Smith, F. Werner, V. Koch, D. Schreiner, E. Bartoszek, M. Buchi, M. Schmid, D. Breu, K. P. Hartmann, P. Zaytseva, D. S. Thommen, , A. Zippelius

The paper shows that CCL5-producing tissue-resident NK cells are critical for IL-12-mediated anti-tumor immunity and that CCL5 delivery can overcome resistance in tumors with low trNK cell infiltration.

bioRxiv · May 27, 2021 · PreprintImmunology