Author

G. Gerold

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

F. J. Zapatero-Belinchon· 2 shared A. Matthaei· 1 shared A. P. Gunesch· 1 shared A. Pich· 1 shared A. Richter· 1 shared A. Viejo-Borbolla· 1 shared B. Mhlekude· 1 shared B. Muhlemann· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

F. J. Zapatero-Belinchon

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Efficient clathrin-mediated entry of enteric adenoviruses in human duodenal cells

M. Becker, N. Dorma, D. V. Conca, N. Mistry, M. Bally, N. Arnberg, G. Gerold

This study identifies clathrin- and dynamin-dependent pathways for efficient enteric adenovirus entry in human duodenal cells, highlighting kinetic advantages over other cell types.

bioRxiv · Mar 6, 2023Microbiology

Innate immune response to SARS-1 CoV-2 infection contributes to neuronal damage in human iPSC-derived peripheral neurons

V. Passos, L. M. Henkel, J. Wang, F. J. Zapatero-Belinchon, R. Moeller, G. Sun, I. Waltl, B. Ritter, K. A. Kropp, S. Zhu, M. Deleidi, U. Kalinke, G. Hoeglinger, G. Gerold, F. Wegner, A. Viejo-Borbolla

This study infects human iPSC-derived CNS and PNS neurons with SARS-CoV-2 and finds that PNS neurons experience more severe neurodegeneration linked to innate immune activation.

bioRxiv · Nov 18, 2022Microbiology

Pharmacological inhibition of bromodomain and extra-terminal proteins induces NRF-2-mediated inhibition of SARS-CoV-2 replication and is subject to viral antagonism

B. Mhlekude, D. Postmus, J. Weiner, S. Stenzel, F. J. Zapatero-Belinchon, R. Olmer, J. Jansen, A. Richter, J. Heinze, N. Heinemann, B. Muhlemann, S. Schroeder, T. C. Jones, M. A. Muller, C. Drosten, , C. Goffinet

This study shows JQ-1 inhibits SARS-CoV-2 replication via NRF-2 activation but is counteracted by viral antagonism, leading to transient antiviral effects.

bioRxiv · Sep 22, 2022 · PreprintMicrobiology

Repurposing screen highlights broad-spectrum coronavirus antivirals and their host targets

S. Haid, A. Matthaei, M. Winkler, S. M. Sake, A. P. Gunesch, J. Rueckert, G. Vieyres, D. Kuehl, T.-T. Nguyen, L. Lasswitz, F. Zapatero, G. Brogden, G. Gerold, B. Wiegmann, U. Bilitewski, , T. Pietschmann

The paper screens a drug library to identify broad-spectrum coronavirus antivirals and their host targets, finding compounds that inhibit both alpha- and beta-coronaviruses.

bioRxiv · Jul 14, 2021 · PreprintMicrobiology