Author

G. I. Georg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Majumbar· 1 shared A. Yang· 1 shared A. Yu· 1 shared B. S. Magenheimer· 1 shared D. A. Harki· 1 shared D. P. Wallace· 1 shared D. Rasmussen· 1 shared E. B. Faber· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Majumbar

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintJun 30, 2022

Development of allosteric, selective cyclin-dependent kinase 2 (CDK2) inhibitors that are negatively cooperative with cyclin binding and show potential as contraceptive agents

E. B. Faber, J. Tang, E. Roberts…·G. I. Georg

This paper develops high-affinity, structurally confirmed allosteric CDK2 inhibitors that show negative cooperativity with cyclin binding and demonstrate contraceptive potential in mouse testicular explants.

DOI 10.1101/2022.06.30.497818

mouseexperimental assay

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivSep 9, 2020

The Lonidamine Derivative H2-Gamendazole Reduces Cyst Formation in Polycystic Kidney Disease

S. V. Sundar, X. Zhou, B. S. Magenheimer…·J. P. Calvet

This study shows that H2-GMZ reduces cyst formation in ADPKD by inhibiting Cl- secretion, cell proliferation, and motility in both in vitro and in vivo models.

DOI 10.1152/ajprenal.00095.2022

humanmouse

𝕏 PostBluesky