Author

G. Keller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

I. Fernandes· 3 shared M. Radisic· 2 shared S. Funakoshi· 2 shared A. Ding· 1 shared A. Prowse· 1 shared A. Witty· 1 shared B. Sun· 1 shared C. A. Simmons· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersBioengineering

I. Fernandes

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Single-nucleotide-resolution genomic maps of O6-methylguanine from the glioblastoma drug temozolomide

J. Buechel, C. Mingard, V. Takhaveev, P. B. Reinert, G. Keller, T. Kloter, S. Huber, M. McKeague, S. J. Sturla

This paper introduces O6-MeG-seq, a method to map O6-methylguanine at single-nucleotide resolution, and shows MGMT does not preferentially repair O6-MeG based on sequence context or chromatin state.

bioRxiv · Dec 12, 2023Cancer Biology

Modeling cardiac fibroblast heterogeneity from human pluripotent stem cell-derived epicardial cells

I. Fernandes, S. Funakoshi, H. Hamidzada, S. Epelman, G. Keller

The paper models cardiac fibroblast heterogeneity using human pluripotent stem cell-derived epicardial cells and shows high heterogeneity similar to human heart fibroblasts.

bioRxiv · Oct 22, 2023Cell Biology

Non-invasive quantification of contractile dynamics in cardiac cells, spheroids and organs-on-a-chip using high frequency ultrasound

E. M. Strohm, N. I. Callaghan, N. Latifi, N. Rafatian, S. Funakoshi, I. Fernandes, M. Radisic, G. Keller, M. Kolios, C. A. Simmons

This paper develops a high-frequency ultrasound technique to non-invasively measure contractile dynamics in cardiac cells, spheroids, and organs-on-a-chip, showing its ability to quantify beat rate, rhythm, and force with high temporal resolution.

bioRxiv · Jun 28, 2022 · PreprintBioengineering

Generation of functional ciliates cholangiocytes from human pluripotent stem cells

M. Ogawa, J.-X. Jiang, S. Xia, D. Yang, A. Ding, O. Laselva, S. Chin, M. Hernandez, C. Cui, Y. Higuchi, H. Suemizu, C. Dorrell, M. Grompe, C. Bear, G. Keller, S. Ogawa

This study generates functional cholangiocytes from human pluripotent stem cells that exhibit mature characteristics and can be used for drug testing and disease modeling.

bioRxiv · Mar 23, 2021Cell Biology

Functional arrays of human pluripotent stem cell-derived cardiac microtissues

N. Thavandiran, C. Hale, P. Blit, M. L. Sandberg, M. E. McElvain, M. Gagliardi, B. Sun, A. Witty, G. Graham, M. McIntosh, M. A. Bakooshli, H. Le, J. Ostblom, S. McEwen, E. Chau, , P. Zandstra

This paper develops a 96-well platform of cardiac microtissues to measure contractile force for drug screening and tissue engineering.

bioRxiv · Mar 5, 2019Bioengineering