G. Graham

IL-27 maintains cytotoxic Ly6C+ gamma delta T cells that arise from immature precursors

The paper identifies immature and mature subsets of IFNγ-producing γδ T cells, showing IL-27 supports cytotoxic function in mature cells but not immature ones.

Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate wide-spread non-receptor mediated immune cell recruitment

The paper shows CXCL4 binds to extracellular matrix proteoglycans, increasing vascular permeability and recruiting various leukocytes through a non-canonical mechanism.

Reproductive resilience but not root architecture underpin yield improvement in maize

This study shows that yield improvement in maize is driven by reproductive resilience rather than changes in root architecture or water capture.

Chemokine receptors ACKR2 and CCR1 coordinate macrophage dynamics and mammary gland development

The paper shows ACKR2 and CCR1 regulate macrophage dynamics and mammary gland development by controlling CCL7 levels and macrophage movement.

A novel methodology for defining stromal expression of atypical chemokine receptors in vivo

This paper introduces a novel method to detect atypical chemokine receptor expression on stromal cells using Alexa-Fluor labelled chemokine ligands, demonstrating ACKR2 expression on blood endothelial cells in the lung.

Functional arrays of human pluripotent stem cell-derived cardiac microtissues

This paper develops a 96-well platform of cardiac microtissues to measure contractile force for drug screening and tissue engineering.

Discovery of the role of a SLOG superfamily biological conflict systems associated protein IodA (YpsA) in oxidative stress protection and cell division inhibition in Gram-positive bacteria

This paper identifies YpsA, a SLOG superfamily protein in Bacillus subtilis, as a regulator of cell division and oxidative stress response, with conserved function in Staphylococcus aureus.