Author

G. Rangarajan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

H. Levine· 2 shared M. K. Jolly· 2 shared P. Kulkarni· 2 shared A. Grishaev· 1 shared A. Mohanty· 1 shared A. Nam· 1 shared A. Nathan· 1 shared E. Massarelli· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

H. Levine

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2 papers

Recent·Most cited

Suppressing chemoresistance in lung cancer via dynamic phenotypic switching and intermittent therapy

A. Nam, A. Mohanty, S. Bhattacharya, S. Kotnala, S. Achuthan, K. Hari, A. Nathan, G. Rangarajan, E. Massarelli, H. Levine, M. K. Jolly, P. Kulkarni, R. Salgia

This study shows that intermittent chemotherapy can suppress chemoresistance in lung cancer by preventing the emergence of tolerant cells through dynamic phenotypic switching.

bioRxiv · Apr 6, 2020Cancer Biology

PAGE4 and Conformational Switching: Insights from Molecular Dynamics Simulations and Implications for Prostate Cancer

X. Lin, S. Roy, M. K. Jolly, F. Bocci, N. Schafer, M.-Y. Tsai, Y. Chen, Y. He, A. Grishaev, K. Weninger, J. Orban, P. Kulkarni, G. Rangarajan, H. Levine, J. N. Onuchic

This study uses molecular dynamics simulations to investigate how phosphorylation of PAGE4 affects its structure and interactions with AP-1 and AR, revealing conformational switching linked to prostate cancer progression.

bioRxiv · Feb 22, 2018Biophysics