Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
10 papers
Recent·Most cited
C. A. Donado, A. H. Jonsson, E. Theisen, F. Zhang, A. Nathan, K. Rupani, D. Jones, Accelerating Medicines Partnership RA/SLE Network, S. Raychaudhuri, D. F. Dwyer, M. B. Brenner
This study identifies granzyme K as a driver of a novel complement activation pathway independent of classical, lectin, or alternative pathways.
bioRxiv · May 22, 2024Immunology
L. Bricio Moreno, J. Barreto de Albuquerque, J. M. Neary, T. Nguyen, K. M. Hastie, S. Landeras-Bueno, C. Hariharan, A. Nathan, M. A. Getz, A. C. Gayton, A. Khatri, G. D. Gaiha, E. O. Saphire, A. D. Luster, J. J. Moon
The paper identifies SARS-CoV-2 BA.1 epitopes recognized by mouse CD4+ T cells and generates corresponding tetramer reagents for studying immune responses.
bioRxiv · Nov 16, 2023 · PreprintImmunology
K. A. Lagattuta, A. Nathan, L. Rumker, M. E. Birnbaum, S. Raychaudhuri
The study identifies TCR sequence features that influence T cell memory formation and positive selection across different T cell lineages.
bioRxiv · Jul 20, 2023Immunology
K. Weinand, S. Sakaue, A. Nathan, A. H. Jonsson, F. Zhang, G. F. M. Watts, Z. Zhu, Accelerating Medicines Partnership Program: RA and SLE Network, D. A. Rao, J. H. Anolik, M. B. Brenner, L. T. Donlin, K. Wei, S. Raychaudhuri
The paper identifies chromatin classes in RA synovial tissue and links them to transcriptional cell states and genetic variants.
bioRxiv · Apr 7, 2023 · PreprintImmunology
G. S. Dunlap, A. Wagner, N. Meednu, F. Zhang, A. H. Jonsson, K. Wei, S. Sakaue, A. Nathan, Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (A, V. P. Bykerk, L. T. Donlin, S. M. Goodman, G. S. Firestein, D. L. Boyle, V. M. Holers, , J. Anolik
This study uses single-cell antigen receptor profiling to identify clonal relationships and functional states of T and B cells in RA synovium.
bioRxiv · Mar 18, 2023 · PreprintImmunology
K. A. Lagattuta, J. B. Kang, A. Nathan, K. E. Pauken, A. H. Jonsson, D. A. Rao, K. Ishigaki, S. Raychaudhuri
The paper identifies TCR sequence features that influence T cell fate by analyzing TCR sequences from human cells and developing a scoring system for regulatory potential.
bioRxiv · Jun 23, 2021Immunology
A. Nathan, J. I. Beynor, Y. Baglaenko, S. Suliman, K. Ishigaki, S. Asgari, C.-C. Huang, Y. Luo, Z. Zhang, K. Lopez Tamara, J. Jimenez, R. I. Calderon, L. Lecca, I. van Rhijn, B. Moody, , S. Raychaudhuri
The paper uses multimodal single-cell profiling to identify a reduction in a polyfunctional Th17-like memory T cell state associated with tuberculosis progression.
bioRxiv · Apr 23, 2020 · PreprintImmunology
A. Nam, A. Mohanty, S. Bhattacharya, S. Kotnala, S. Achuthan, K. Hari, A. Nathan, G. Rangarajan, E. Massarelli, H. Levine, M. K. Jolly, P. Kulkarni, R. Salgia
This study shows that intermittent chemotherapy can suppress chemoresistance in lung cancer by preventing the emergence of tolerant cells through dynamic phenotypic switching.
bioRxiv · Apr 6, 2020Cancer Biology
A. Mohanty, A. Nam, A. Pozhitkov, S. Bhattacharya, L. Yang, A. Nathan, X. Wu, S. Srivastava, I. Mambetsariev, M. Nelson, R. Pangeni, D. Raz, Y. Chen, Y. He, J. Orban, , R. Salgia
This study identifies a non-genetic mechanism for cisplatin resistance in lung adenocarcinoma involving the integrin β4/paxillin axis and its regulation of USP1 and VDAC1.
bioRxiv · Sep 25, 2019Cancer Biology
A. Kalvala, P. Wallet, L. Yang, C. Wang, H. Li, A. Nam, A. Nathan, I. Mambetsariev, V. Poroyko, H. Gao, P. Chu, M. Sattler, A. Bild, E. R. Manuel, P. P. Lee, , R. Salgia
The paper shows mutant KRAS induces T cells to become immune-suppressive Treg-like cells through exosomes, sera, or direct transfection, with single-cell sequencing identifying the interferon pathway as the mechanism.
bioRxiv · Sep 11, 2019Cancer Biology