Author

G. Rupprecht

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Hsu· 2 shared A. Agarwal· 1 shared A. Dohlman· 1 shared A. Lazarides· 1 shared C. Eward· 1 shared C. Hsu· 1 shared D. Sivaraj· 1 shared E. Altunel· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

D. Hsu

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2 papers

Recent·Most cited

Chromatin Remodeling in Patient-Derived Colorectal Cancer Models

K. Xiang, E. Wang, G. Rupprecht, J. Mantyh, M. Negrete, G. Sanati, C. Hsu, P. Randon, A. Dohlman, K. Kretzschmar, N. Giroux, S. Ding, L. Wang, J. Prado, Q. Huang, , X. Shen

This study compares chromatin remodeling in colorectal cancer patient-derived models and identifies transcription factors driving differences in growth and drug response.

bioRxiv · Jul 24, 2022Cancer Biology

A cross-species drug discovery pipeline to identify and validate new treatments for osteosarcoma

J. Somarelli, G. Rupprecht, E. Altunel, E. Flamant, S. R. Rao, D. Sivaraj, A. Lazarides, S. Hoskinson, M. Sheth, S. Cheng, S. Y. Kim, K. Ware, A. Agarwal, M. Cullen, L. Selmic, , D. Hsu

This study develops a cross-species drug discovery pipeline to identify and validate new treatments for osteosarcoma, finding that dual inhibition of proteasome and CRM1 pathways induces synergistic cytotoxicity.

bioRxiv · Oct 19, 2020Cancer Biology