SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells
Y. Wang, F. S. Yen, X. G. Zhu, R. C. Timson, R. Weber, C. Xing, Y. Liu, B. Allwein, H. Luo, H.-W. Yeh, S. Heissel, G. Unlu, E. R. Gamazon, M. G. Kharas, R. Hite, K. Birsoy
This study identifies SLC25A39 as a mitochondrial glutathione importer and shows its role in cell proliferation and red blood cell development, with GSH availability regulating its abundance.
bioRxiv · Sep 15, 2021Biochemistry