Systematic Discovery of the Functional Impact of Somatic Genome Alterations in Individual Tumors through Tumor-specific Causal Inference
C. Cai, G. Cooper, K. Lu, X. Ma, S. Xu, Z. Zhao, X. Chen, Y. Xue, A. Lee, N. Clark, V. Chen, S. Lu, L. Chen, L. Yu, H. Hochheiser, , X. Lu
This paper introduces a tumor-specific causal inference framework to identify causative somatic genome alterations and their impact on molecular phenotypes in individual tumors.
bioRxiv · May 24, 2018Cancer Biology