H. K. Lee

The paper identifies SCOOP-MIK2 binding mechanisms using in silico analysis, AlphaFold-Multimer, and experimental validation, revealing conserved binding pockets and their functional importance.

This study identifies new roles for Arabidopsis LRR-MAL receptor-like kinases in regulating early pollen-stigma interactions, supporting intraspecies fertilization and blocking interspecies hybridization.

The paper identifies RALF22 as a peptide that functions both structurally and signaling in plant cell wall assembly, forming complexes with LRX1 and LLG1-FER to regulate cell expansion.

This study identifies CEPs as immune-modulatory peptides in Arabidopsis that coordinate immunity with nitrogen status through receptor-dependent mechanisms.

This paper enhances fluorescence detection using photonic-plasmonic coupling, achieving ultrasensitive protein detection with a 52-fold signal boost and 10 fg/ml detection limit.

This paper develops a deep learning pipeline to detect malignant glands in prostate cancer core needle biopsies, achieving high accuracy and providing heatmaps for pathologists.

This paper develops a deep multiple instance learning model to predict tumor purity from histopathology slides, showing spatial variation and improving sample selection for genomic analysis.

The paper reanalyzes scRNA-seq data to show that severe SARS-CoV-2 infection is associated with more activated B cells and pro-inflammatory macrophages.

This study identifies two stem-like gastric cancer subpopulations with distinct chemoresistance and survival outcomes using scRNA-seq and organoid models.

This study identifies two groups of Arabidopsis receptor kinases that regulate intraspecies pollen tube growth in the female reproductive tract and contribute to interspecies reproductive barriers.

This study identifies E6-like 1 (E6L1) as a novel gene in Arabidopsis thaliana involved in early pollen-stigma interactions, with mutants showing mild impairments in pollen hydration and seed set.

The paper identifies Daam2 as a factor promoting glioma formation by suppressing VHL expression through ubiquitination and degradation.