Author

B. Deneen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell-cell communication· 2 Organism:mouse· 2

Frequent Co-Authors

B. Lozzi· 3 shared G. Rao· 3 shared P. He· 3 shared Y. Ko· 3 shared A. Jalali· 2 shared A. O. Harmanci· 2 shared A. Serin Harmanci· 2 shared C. Mohila· 2 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

B. Lozzi

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6 papers

Recent·Most cited

A neurovascular progenitor sits at the nexus of glioblastoma lineage trajectories

E. Fazzari, D. J. Azizad, K. Yu, W. Ge, M. X. Li, P. R. Nano, S. Baisiwala, A. Martija, R. L. Kan, J. Caston, L. N. Diafos, H. A. Tum, C. Tse, N. A. Bayley, V. Haka, , A. Bhaduri

This study identifies a neurovascular progenitor cell type in glioblastoma that links distinct malignant lineages and influences tumor composition and survival.

bioRxiv · Jul 24, 2024 · PreprintCancer Biology

Integrated electrophysiological and genomic profiles of single cells reveal spiking tumor cells in human glioma

R. N. Curry, Q. Ma, M. F. McDonald, Y. Ko, S. Srivastava, P.-S. Chin, P. He, B. Lozzi, J. Jing, P. Athukuri, S. Wang, A. O. Harmanci, B. Arenkiel, X. Jiang, B. Deneen, , A. Serin Harmanci

The paper identifies hybrid cells in human glioma with both neuronal and glial electrophysiological and transcriptomic features using Patch-sequencing and a new computational tool.

bioRxiv · Mar 2, 2024Cancer Biology

Remote neuronal activity drives glioma infiltration via Sema4f

E. Huang-Hobbs, Y.-T. Cheng, Y. Ko, E. Luna-Figueroa, B. Lozzi, K. Taylor, M. McDonald, P. He, H.-C. Chen, Y. Yang, E. Maleki, Z.-F. Lee, S. Murali, M. Williamson, D. Choi, , B. Deneen

This study identifies callosal projection neurons as drivers of glioma infiltration through Sema4F-mediated activity-dependent signaling in mouse and human tumors.

bioRxiv · Mar 15, 2023 · PreprintCancer Biology

Identification of functional immune and neuronal tumor cells in glioma

R. N. Curry, M. F. McDonald, Q. Ma, J. Meyer, I. Aiba, B. Lozzi, A. Cervantes, Y. Ko, E. Luna-Figueroa, D.-J. Choi, Z.-F. Lee, J. Jing, A. O. Harmanci, A. Rosenbaum, P. He, , A. Serin Harmanci

The paper introduces SCRAM, a tool that identifies tumor-specific cell types in glioma with functional properties similar to non-tumor cells.

bioRxiv · Nov 5, 2022 · PreprintCancer Biology

Glioblastoma disrupts cortical network activity at multiple spatial and temporal scales

J. Meyer, K. Yu, E. Luna Figueroa, B. Deneen, J. Noebels

This study investigates how glioblastoma disrupts cortical network activity, showing increased neural hyperexcitability and abnormal glutamate accumulation during tumor progression.

bioRxiv · Aug 31, 2022 · PreprintCancer Biology

Daam2 Driven Degradation Of VHL Promotes Gliomagenesis

W. Zhu, S. Krishna, C. Garcia, C.-C. J. Lin, K. L. Scott, C. Mohila, C. Creighton, S.-H. Yoo, H. K. Lee, B. Deneen

The paper identifies Daam2 as a factor promoting glioma formation by suppressing VHL expression through ubiquitination and degradation.

bioRxiv · May 19, 2017Cancer Biology