Author

S. Shepherd

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Y. Xiong· 3 shared B. Cunningham· 2 shared T. Song· 2 shared X. Wang· 2 shared A. Dwivedy· 1 shared A. Hines· 1 shared A. J. R. Heck· 1 shared B. T. Cunningham· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersBioengineering

Y. Xiong

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Designer DNA NanoGripper

L. Zhou, Y. Xiong, L. Cooper, S. Shepherd, T. Song, A. Dwivedy, L. Rong, T. Wang, B. Cunningham, X. Wang

The paper designs, synthesizes, and characterizes a DNA nanorobot, NanoGripper, capable of capturing viral particles and functioning as a biosensor for SARS-CoV-2 detection in human saliva.

bioRxiv · Apr 26, 2023 · PreprintBioengineering

Muscle of obese insulin-resistant humans exhibits losses in proteostasis and attenuated proteome dynamics that are improved by exercise training.

K. Srisawat, C. A. Stead, K. Hesketh, M. Pogson, J. A. Strauss, M. Cocks, I. Siekmann, S. M. Phillips, P. J. Lisboa, S. Shepherd, J. G. Burniston

This study examines muscle proteostasis in obese insulin-resistant individuals and finds that endurance exercise improves proteome dynamics and proteostasis.

bioRxiv · Mar 16, 2023 · PreprintPhysiology

Target Recycling Amplification Process for Digital Detection of Exosomal MicroRNAs Through Photonic Resonator Absorption Microscopy

X. Wang, S. Shepherd, N. Li, C. Che, T. Song, Y. Xiong, I. R. Palm, B. Zhao, M. Kohli, U. Demirci, Y. Lu, B. Cunningham

This paper introduces TRAP, a method for detecting exosomal miRNAs with high sensitivity and selectivity, showing improved detection limits compared to qRT-PCR.

bioRxiv · Dec 7, 2022Bioengineering

Photonic-Plasmonic Coupling Enhanced Fluorescence Enabling Digital-Resolution Ultrasensitive Protein Detection

P. Barya, Y. Xiong, S. Shepherd, R. Gupta, L. D. Akin, J. Tibbs, H. K. Lee, S. Singamaneni, B. T. Cunningham

This paper enhances fluorescence detection using photonic-plasmonic coupling, achieving ultrasensitive protein detection with a 52-fold signal boost and 10 fg/ml detection limit.

bioRxiv · Oct 29, 2022Bioengineering

Spectral Interferences Impede the High-Resolution Mass Analysis of Recombinant Adeno-Associated Viruses

V. C. Yin, P. Devine, J. Saunders, A. Hines, S. Shepherd, M. Dembek, C. Dobson, J. Snijder, N. Bond, A. J. R. Heck

The paper characterizes recombinant adeno-associated viruses (rAAVs) using native mass spectrometry, revealing spectral interferences caused by heterogeneity and charging behavior.

bioRxiv · Aug 27, 2022 · PreprintBiochemistry