Author

H. Kitano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Blanco-Miguez· 1 shared A. Cereseto· 1 shared A. Silverj· 1 shared A. T. Satpathy· 1 shared A. Visconti· 1 shared A. Y. Chen· 1 shared B. Daniel· 1 shared C. Huttenhower· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Blanco-Miguez

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Discovering and exploring the hidden diversity of human gut viruses using highly enriched virome samples

M. Zolfo, A. Silverj, A. Blanco-Miguez, P. Manghi, O. Rota-Stabelli, V. Heidrich, J. Jensen, S. Maharjan, E. Franzosa, C. Menni, A. Visconti, F. Pinto, M. Ciciani, C. Huttenhower, A. Cereseto, , N. Segata

The paper presents a method to discover new human gut viruses using enriched virome samples and reports over 162,000 novel viral sequences.

bioRxiv · Feb 19, 2024 · PreprintMicrobiology

Human immune and gut microbial parameters associated with inter-individual variations in COVID-19 mRNA vaccine-induced immunity

M. Hirota, M. Tamai, S. Yukawa, N. Taira, M. M. Matthews, T. Toma, Y. Seto, M. Yoshida, S. Toguchi, M. Miyagi, T. Mori, H. Tomori, O. Tamai, M. Kina, E. Sakihara, , H. Ishikawa

The paper identifies baseline AP-1 gene expression and gut microbial fucose/rhamnose degradation as factors negatively correlated with BNT162b2 mRNA vaccine-induced T-cell responses.

bioRxiv · Aug 8, 2022 · PreprintImmunology

Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting

J. Wei, P. Lotfy, K. Faizi, S. Baungaard, E. Gibson, E. Wang, H. Slabodkin, E. Kinnaman, S. Chandrasekaran, H. Kitano, M. G. Durrant, C. V. Duffy, P. D. Hsu, S. Konermann

The paper develops a deep learning model to predict CRISPR-Cas13d guide RNA efficiency and identifies novel orthologs with improved specificity and reduced toxicity for RNA targeting.

bioRxiv · Sep 14, 2021Bioengineering

Macrophage inflammatory and regenerative response periodicity is programmed by cell cycle and chromatin state

B. Daniel, J. A. Belk, S. L. Meier, A. Y. Chen, K. Sandor, Y. Qi, H. Kitano, J. R. Wheeler, D. S. Foster, M. S. Januszyk, M. T. Longaker, H. Y. Chang, A. T. Satpathy

This study shows that macrophage inflammatory and regenerative responses are phase-dependent on the cell cycle, with S-G2/M phases linked to tissue remodeling and reduced IFNG-induced repolarization.

bioRxiv · Jun 24, 2021Immunology