Author

H. Krause

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

J. Liu· 2 shared A. Balasubramanian· 1 shared A. Delmas-Eliason· 1 shared A. R. Burns· 1 shared A. Rodriguez-Palacios· 1 shared A. S. Vaidya· 1 shared a. spicakova· 1 shared B. M. Palmeira· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersPhysiology

J. Liu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Quantifying forms and functions of intestinal bile acid pools in mice

K. Sudo, A. Delmas-Eliason, S. Soucy, K. E. Barrack, J. Liu, A. Balasubramanian, C. J. Shu, M. James, C. L. Hegner, H. D. Dionne, A. Rodriguez-Palacios, H. Krause, G. A. O'Toole, S. J. Karpen, P. A. Dawson, , M. S. Sundrud

The paper quantifies ileal bile acid pools in mice and shows that Asbt-mediated transport dominates their size and composition, with loss of Asbt reducing pool size and altering transcriptional responses.

bioRxiv · Feb 16, 2024 · PreprintPhysiology

In Vitro Safety Signals for Potential Clinical Development of the Anti-Inflammatory Pregnane X Receptor Agonist FKK6

Z. Dvorak, B. Vyhlidalov, P. Pecinkov, H. Li, P. Anzenbacher, a. spicakova, e. anzenbacherova, V. Chow, J. LIU, H. Krause, D. J. Wilson, T. Beres, P. Tarkowski, D. Chen, S. Mani

This paper performs in vitro pharmacological profiling of FKK6, showing high PXR selectivity, intestinal permeability, and rapid metabolism, supporting its potential preclinical development.

bioRxiv · Oct 21, 2023Biochemistry

Selective Control of Parasitic Nematodes Using Bioactivated Nematicides

A. R. Burns, R. J. Ross, M. Kitner, J. Volpatti, A. S. Vaidya, E. Puumala, B. M. Palmeira, E. M. Redman, J. Snider, S. Marwah, S. W. Chung, M. H. MacDonald, J. Tiefenbach, C. Hu, Q. Xiao, , P. Roy

This study identifies selectivins, a family of imidazothiazole nematicides that are selectively activated in nematodes, offering effective and selective control of plant-parasitic nematodes.

bioRxiv · Mar 11, 2022 · PreprintPharmacology & Toxicology

15-keto-prostaglandin E2 activates host peroxisome proliferator-activated receptor gamma (PPAR-γ) to promote Cryptococcus neoformans growth during infection.

R. J. Evans, K. Pline, C. Loynes, S. Needs, M. Aldrovandi, J. Tifenbach, E. Bielska, R. Rubino, C. Nicol, R. C. May, H. Krause, V. O'Donnell, S. Renshaw, S. Johnston

bioRxiv · Jan 23, 2019Microbiology