Author

H. L. Sweeney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Y. i. Lee· 2 shared A. David· 1 shared A. Di Cicco· 1 shared A. Houdusse· 1 shared C. C. Hart· 1 shared C. Delevoye· 1 shared C. Kikuti· 1 shared D. Levy· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

Y. i. Lee

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Myospreader improves gene editing in skeletal muscle by myonuclear propagation

K. Poukalov, M. C. Valero, D. Muscato, L. Adams, H. Chun, Y. i. T. Lee, N. Andrade, Z. Zeier, H. L. Sweeney, E. T. Wang

Myospreader enhances CRISPR/Cas9 gene editing in skeletal muscle by promoting myonuclear propagation and improving therapeutic efficacy in mouse models.

bioRxiv · Nov 6, 2023Cell Biology

How Myosin VI Traps its Off-State, is Activated and Dimerizes

L. Canon, C. Kikuti, V. J. Planelles-Herrero, T. Lin, F. Mayeux, H. Sirkia, Y. i. Lee, L. Heidsieck, L. Velikovsky, A. David, X. Liu, D. Moussaoui, E. Forest, P. Hook, K. J. Petersen, , A. Houdusse

This study investigates how Myosin VI is trapped in its off-state, activated, and dimerizes through structural and functional analyses of its interactions with partners.

bioRxiv · Jun 30, 2023Biochemistry

Evaluation of the DBA/2J mouse as a potential background strain for genetic models of cardiomyopathy

C. C. Hart, Y. i. Lee, D. W. Hammers, H. L. Sweeney

The study evaluates the DBA/2J mouse as a background strain for genetic models of cardiomyopathy and finds no evidence of hypertrophic cardiomyopathy or other cardiac pathologies.

bioRxiv · May 16, 2022Physiology