Author

H. Rao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:genetic perturbation / CRISPR· 2 Organism:mouse· 2

Frequent Co-Authors

L. Li· 4 shared W.-Q. Gao· 4 shared J. Liu· 3 shared J. Xu· 3 shared M. Liu· 3 shared W. Feng· 3 shared X. Li· 3 shared A. C. Sims· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersCancer Biology

L. Li

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Multilevel regulation of NF-kappa B signaling by NSD2 suppresses Kras-driven pancreatic tumorigenesis

W. Feng, N. Niu, P. Lu, H. Rao, Z. Chen, W. Zhang, C. Ma, C. Liu, Y. Xu, W.-Q. Gao, J. Xue, L. Li

This study shows NSD2 acts as a tumor suppressor in Kras-driven pancreatic cancer by regulating NF-kappa B signaling through multiple mechanisms.

bioRxiv · Sep 11, 2023 · PreprintCancer Biology

Host network-based discovery of critical regulators of innate immunity, virus growth, and pathogenesis in influenza virus infection

A. J. Eisfeld, S. Fan, H. Rao, B. A. Venkatachalam, D. W. Smith, P. J. Halfmann, K. B. Walters, S. Nair, L. B. Thackray, J. F. Kocher, A. C. Sims, H. D. Mitchell, G. Neumann, V. Blank, K. M. Waters, , Y. Kawaoka

The paper identifies novel innate immune regulators affecting influenza virus replication and pathogenesis through experimental validation of network model predictions.

bioRxiv · Aug 29, 2022 · PreprintMicrobiology

The Histone Methyltransferase SETD2 Modulates Oxidative Stress to Attenuate Colonic Inflammation and Tumorigenesis in Mice

M. Liu, H. Rao, J. Liu, X. Li, W. Feng, J. Xu, L. Li, W.-Q. Gao

This study shows that SETD2 deficiency in mice worsens colonic inflammation and tumorigenesis by increasing oxidative stress and impairing epithelial barrier function.

Redox Biology · Jul 1, 2021Peer-reviewedCell Biology

SETD2 deficiency impairs β-catenin destruction complex to facilitate renal cell carcinoma formation

H. Rao, X. Li, m. liu, J. Liu, W. Feng, J. Xu, W.-Q. Gao, L. Li

This study shows that SETD2 deficiency disrupts the β-catenin destruction complex, promoting ccRCC formation, and links SETD2-mediated H3K36me3 to Wnt/β-catenin signaling in renal cancer.

bioRxiv · Jul 13, 2020 · PreprintCancer Biology

Di-Ras2 Promotes Renal Cell Carcinoma Formation by Activating the MAPK Pathway in the Absence of VHL

H. Rao, X. Li, M. Liu, J. Liu, X. Li, J. Xu, L. Li, W.-Q. Gao

This study identifies Di-Ras2 as an oncogene in ccRCC that promotes tumor formation by activating the MAPK pathway in the absence of VHL.

bioRxiv · Jun 27, 2019 · PreprintCancer Biology